Recent advances in research on lignans and neolignans

RB Teponno, S Kusari, M Spiteller - Natural product reports, 2016 - pubs.rsc.org
Covering: 2009 to 2015 Lignans and neolignans are a large group of natural products
derived from the oxidative coupling of two C6–C3 units. Owing to their biological activities …

Chromone as a privileged scaffold in drug discovery: recent advances: miniperspective

J Reis, A Gaspar, N Milhazes… - Journal of medicinal …, 2017 - ACS Publications
The use of privileged structures in drug discovery has proven to be an effective strategy,
allowing the generation of innovative hits/leads and successful optimization processes …

Total syntheses and anti-inflammatory activities of syringin and its natural analogues

H Dong, M Wu, Y Wang, W Du, Y He… - Journal of Natural …, 2021 - ACS Publications
Syringin (1), a natural bioactive glucoside isolated from the root of Acanthopanax senticosus
(Rupr. Maxim.) Harms, possesses significant anti-inflammatory activity. In this study, we have …

Naturally occurring chromone glycosides: Sources, bioactivities, and spectroscopic features

Y Amen, M Elsbaey, A Othman, M Sallam, K Shimizu - Molecules, 2021 - mdpi.com
Chromone glycosides comprise an important group of secondary metabolites. They are
widely distributed in plants and, to a lesser extent, in fungi and bacteria. Significant …

Synthesis of neolignans as microtubule stabilisers

BS Kumar, A Singh, A Kumar, J Singh… - Bioorganic & Medicinal …, 2014 - Elsevier
Tubulin is a well established target for anticancer drug development. Lignans and
neolignans were synthesized as tubulin interacting agents. Neolignans 10 and 19 exhibited …

Update on naturally occurring novel arylnaphthalenes from plants

S Li, Z Liang, J Li, X Zhang, R Zheng, C Zhao - Phytochemistry reviews, 2020 - Springer
Arylnaphthalene compounds, also called cyclolignolides, are lignans and have been
extensively studied and documented, especially podophyllotoxin and its derivatives. Great …

Electrooxidative tandem cyclization of enaminones to give 3-arylthiochromone derivatives

P Xu, Z Zhong, H Huang, W Pan, Y Zhang, A Zhou - Tetrahedron, 2022 - Elsevier
A novel and electrooxidative tandem cyclization of enaminones with aryl/alkylthiol and
ArSSAr to 3-arylthiochromone derivatives were reported. Compared to previous methods …

Flavonoids as chemotaxonomic markers in the genus Drosera

C Braunberger, M Zehl, J Conrad, C Wawrosch… - Phytochemistry, 2015 - Elsevier
The botanical classification of the huge genus Drosera remains controversial since long. In
the present study, the pattern of major phenolic compounds in ten Drosera species …

Constituents of the fruits of Rubus chingii Hu and their neuroprotective effects on human neuroblastoma SH-SY5Y cells

J Wang, X Zhang, J Yu, J Du, X Wu, L Chen… - Food Research …, 2023 - Elsevier
Abstract Rubi fructus (Rubus chingii Hu) is a fruit of Rubus genus and is used in medicine
and food applications. In this study, eight new phenylpropanoids (1–8) and seven known …

Macrolobin: A new unusual C-glycoside chromone from Macrolobium latifolium and its anticholinesterase and antimicrobial activities

BO do Nascimento, OC da Silva Neto, MTF Teodoro… - Phytochemistry …, 2020 - Elsevier
This work describes the chemical and biological investigations of leaves and stems of
Macrolobium latifolium (Vogel). The DCM, EtOAc soluble fractions obtained by liquid-liquid …