[HTML][HTML] Pigment epithelium-derived factor and its role in microvascular-related diseases
Y Wang, X Liu, X Quan, X Qin, Y Zhou, Z Liu, Z Chao… - Biochimie, 2022 - Elsevier
Microvascular diseases are among the most clinically important diseases, and vascular
abnormalities are central in the development of such diseases. Pigment epithelium-derived …
abnormalities are central in the development of such diseases. Pigment epithelium-derived …
[HTML][HTML] Overexpression of METTL3 attenuates high-glucose induced RPE cell pyroptosis by regulating miR-25-3p/PTEN/Akt signaling cascade through DGCR8
X Zha, X Xi, X Fan, M Ma, Y Zhang, Y Yang - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Abstract Methyltransferase-like protein 3 (METTL3) regulates multiple cell functions and
diseases by modulating N 6-methyladenosine (m 6 A) modifications. However, it is still …
diseases by modulating N 6-methyladenosine (m 6 A) modifications. However, it is still …
Adipose mesenchymal stem cells‐secreted extracellular vesicles containing microRNA‐192 delays diabetic retinopathy by targeting ITGA1
C Gu, H Zhang, Y Gao - Journal of cellular physiology, 2021 - Wiley Online Library
Diabetic retinopathy (DR) has characteristics of early loss of capillary pericytes, contributing
to aberrant endothelial proliferation and angiogenesis. The function of extracellular vesicles …
to aberrant endothelial proliferation and angiogenesis. The function of extracellular vesicles …
TREM-2-p38 MAPK signaling regulates neuroinflammation during chronic cerebral hypoperfusion combined with diabetes mellitus
J Zhang, Y Liu, Y Zheng, Y Luo, Y Du, Y Zhao… - Journal of …, 2020 - Springer
Background Diabetes mellitus (DM) and chronic cerebral hypoperfusion (CCH) are both risk
factors for cognitive impairment. However, whether DM and CCH can synergistically …
factors for cognitive impairment. However, whether DM and CCH can synergistically …
Rice bran and vitamin B6 suppress pathological neovascularization in a murine model of age-related macular degeneration as novel HIF inhibitors
Pathological neovascularization in the eye is a leading cause of blindness in all age groups
from retinopathy of prematurity (ROP) in children to age-related macular degeneration …
from retinopathy of prematurity (ROP) in children to age-related macular degeneration …
MiR-192 attenuates high glucose-induced pyroptosis in retinal pigment epithelial cells via inflammasome modulation
C Gu, H Zhang, Q Li, S Zhao, Y Gao - Bioengineered, 2022 - Taylor & Francis
Diabetic retinopathy is one of the most characteristic complications of diabetes mellitus, and
pyroptosis plays acrucial role in the onset and development of diabetic retinopathy. Although …
pyroptosis plays acrucial role in the onset and development of diabetic retinopathy. Although …
Natural plant medications for the treatment of retinal diseases: the blood-retinal barrier as a clue
Y Ren, H Liang, M Xie, M Zhang - Phytomedicine, 2024 - Elsevier
Background Retinal diseases significantly contribute to the global burden of visual
impairment and blindness. The occurrence of retinal diseases is often accompanied by …
impairment and blindness. The occurrence of retinal diseases is often accompanied by …
Caffeine protects against retinal inflammation
F Conti, F Lazzara, GL Romano… - Frontiers in …, 2022 - frontiersin.org
Caffeine, one of the most consumed central nervous system (CNS) stimulants, is an
antagonist of A1 and A2A adenosine receptors. In this study, we investigated the potential …
antagonist of A1 and A2A adenosine receptors. In this study, we investigated the potential …
[HTML][HTML] MiR-130a alleviated high-glucose induced retinal pigment epithelium (RPE) death by modulating TNF-α/SOD1/ROS cascade mediated pyroptosis
X Xi, Y Yang, J Ma, Q Chen, Y Zeng, J Li… - Biomedicine & …, 2020 - Elsevier
High-glucose induced retinal pigment epithelium (RPE) death by triggering oxidative stress,
however, the underlying mechanisms are still not fully delineated. In this study, the RPE cell …
however, the underlying mechanisms are still not fully delineated. In this study, the RPE cell …
Dihydromyricetin alleviates high glucose-induced oxidative stress and apoptosis in human retinal pigment epithelial cells by downregulating miR-34a expression
W Li, H Xiao - Diabetes, Metabolic Syndrome and Obesity, 2021 - Taylor & Francis
Background Diabetic retinopathy (DR) is one of the most common microvascular
complications of diabetes mellitus, which leads to neuronal and vascular dysfunction in the …
complications of diabetes mellitus, which leads to neuronal and vascular dysfunction in the …