Urgency and necessity of Epstein-Barr virus prophylactic vaccines

L Zhong, C Krummenacher, W Zhang, J Hong, Q Feng… - npj Vaccines, 2022 - nature.com
Abstract Epstein-Barr virus (EBV), a γ-herpesvirus, is the first identified oncogenic virus,
which establishes permanent infection in humans. EBV causes infectious mononucleosis …

New look of EBV LMP1 signaling landscape

L Wang, S Ning - Cancers, 2021 - mdpi.com
Simple Summary Epstein-Barr Virus (EBV) infection is associated with various lymphomas
and carcinomas as well as other diseases in humans. The transmembrane protein LMP1 …

Structural basis for genome packaging, retention, and ejection in human cytomegalovirus

Z Li, J Pang, L Dong, X Yu - Nature Communications, 2021 - nature.com
How the human cytomegalovirus (HCMV) genome—the largest among human
herpesviruses—is packaged, retained, and ejected remains unclear. We present the in situ …

Structures of pseudorabies virus capsids

G Wang, Z Zha, P Huang, H Sun, Y Huang… - Nature …, 2022 - nature.com
Pseudorabies virus (PRV) is a major etiological agent of swine infectious diseases and is
responsible for significant economic losses in the swine industry. Recent data points to …

Structure of human cytomegalovirus virion reveals host tRNA binding to capsid-associated tegument protein pp150

YT Liu, D Strugatsky, W Liu, ZH Zhou - Nature Communications, 2021 - nature.com
Under the Baltimore nucleic acid-based virus classification scheme, the herpesvirus human
cytomegalovirus (HCMV) is a Class I virus, meaning that it contains a double-stranded DNA …

EBV infection and its regulated metabolic reprogramming in nasopharyngeal tumorigenesis

T Yang, C You, S Meng, Z Lai, W Ai… - Frontiers in Cellular and …, 2022 - frontiersin.org
Viral oncogenes may drive cellular metabolic reprogramming to modulate the normal
epithelia cell malignant transformation. Understanding the viral oncogene–mediated …

[HTML][HTML] T cell-mediated immunity during Epstein–Barr virus infections in children

M Liu, R Wang, Z Xie - Infection, Genetics and Evolution, 2023 - Elsevier
Epstein–Barr virus (EBV) infection is extremely common worldwide, with approximately 90%
of adults testing positive for EBV antibodies. Human are susceptible to EBV infection, and …

Structures of Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus virions reveal species-specific tegument and envelope features

J Zhen, J Chen, H Huang, S Liao, S Liu, Y Yuan… - Journal of …, 2024 - journals.asm.org
Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV) are
classified into the gammaherpesvirus subfamily of Herpesviridae, which stands out from its …

Ring-stacked capsids of white spot syndrome virus and structural transitions with genome ejection

M Sun, M Liu, H Shan, K Li, P Wang, H Guo, Y Zhao… - Science …, 2023 - science.org
White spot syndrome virus (WSSV) is one of the largest DNA viruses and the major
pathogen responsible for white spot syndrome in crustaceans. The WSSV capsid is critical …

[HTML][HTML] Advancing therapeutic strategies for Epstein-Barr virus-associated malignancies through lytic reactivation

H Tan, Y Gong, Y Liu, J Long, Q Luo, OD Faleti… - Biomedicine & …, 2023 - Elsevier
Epstein-Barr virus (EBV) is a widespread human herpes virus associated with lymphomas
and epithelial cell cancers. It establishes two separate infection phases, latent and lytic, in …