Antimicrobial peptides: features, action, and their resistance mechanisms in bacteria

H Moravej, Z Moravej, M Yazdanparast… - Microbial Drug …, 2018 - liebertpub.com
In recent years, because of increased resistance to conventional antimicrobials, many
researchers have started to study the synthesis of new antibiotics to control the disease …

An overview of antimicrobial peptides and the latest advances in their development

JM Sierra, E Fusté, F Rabanal, T Vinuesa… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: The recent dramatic increase in the incidence of antimicrobial resistance has
been recognized by organizations such as the United Nations and World Health …

A review on antimicrobial peptides databases and the computational tools

S Ramazi, N Mohammadi, A Allahverdi, E Khalili… - Database, 2022 - academic.oup.com
Abstract Antimicrobial Peptides (AMPs) have been considered as potential alternatives for
infection therapeutics since antibiotic resistance has been raised as a global problem. The …

Resistance mechanisms to antimicrobial peptides in gram-positive bacteria

L Assoni, B Milani, MR Carvalho… - Frontiers in …, 2020 - frontiersin.org
With the alarming increase of infections caused by pathogenic multidrug-resistant bacteria
over the last decades, antimicrobial peptides (AMPs) have been investigated as a potential …

Current status on prevention and treatment of canine leishmaniasis

RM Reguera, M Moran, Y Perez-Pertejo… - Veterinary …, 2016 - Elsevier
Canine leishmaniasis (CanL) is a parasite-borne disease mainly induced by Leishmania
infantum in the Old World and Leishmania chagasi (infantum) in the New World. CanL is a …

Conversion of broad-spectrum antimicrobial peptides into species-specific antimicrobials capable of precisely targeting pathogenic bacteria

L Xu, C Shao, G Li, A Shan, S Chou, J Wang, Q Ma… - Scientific Reports, 2020 - nature.com
Currently, the majority of antibiotics in clinical use have broad activity spectra, killing
pathogenic and beneficial microorganisms indiscriminately. The disruption of the ecological …

Rational Design of Dipicolylamine-Containing Carbazole Amphiphiles Combined with Zn2+ as Potent Broad-Spectrum Antibacterial Agents with a Membrane …

J Liu, H Li, H Li, S Fang, J Shi, Y Chen… - Journal of Medicinal …, 2021 - ACS Publications
Antibiotic resistance has become one of the most urgently important problems facing
healthcare providers. A novel series of dipicolylamine-containing carbazole amphiphiles …

Graph-based data integration from bioactive peptide databases of pharmaceutical interest: toward an organized collection enabling visual network analysis

L Aguilera-Mendoza, Y Marrero-Ponce… - …, 2019 - academic.oup.com
Motivation Bioactive peptides have gained great attention in the academy and
pharmaceutical industry since they play an important role in human health. However, the …

Network science and group fusion similarity-based searching to explore the chemical space of antiparasitic peptides

S Ayala-Ruano, Y Marrero-Ponce… - ACS …, 2022 - ACS Publications
Antimicrobial peptides (AMPs) have appeared as promising compounds to treat a wide
range of diseases. Their clinical potentialities reside in the wide range of mechanisms they …

Recent advances in chemotherapeutics for leishmaniasis: Importance of the cellular biochemistry of the parasite and its molecular interaction with the host

R Singh, M Kashif, P Srivastava, PP Manna - Pathogens, 2023 - mdpi.com
Leishmaniasis, a category 1 neglected protozoan disease caused by a kinetoplastid
pathogen called Leishmania, is transmitted through dipteran insect vectors (phlebotomine …