Condensed heterocycles are well-known for their excellent biological effects and they are
undeniably important compounds in organic chemistry. Electrophilic cyclization reactions …

Cancer is still one of the leading causes of death worldwide. Many researchers are working
to design and develop heterocyclic‐based drugs with the potential to treat cancer at various …

4-Phenyl-3-[2-(phenylamino) ethyl]-1 H-1, 2, 4-triazole-5 (4 H)-thione was used as a starting
compound for the synthesis of the corresponding 1, 2, 4-triazol-3-ylthioacetohydrazide …

In order to search for innovative nootropic agents, new 1-benzyl-4-(4-(R)-5-sulfonylidene-4,
5-dihydro-1H-1, 2, 4-triazol-3-yl) pyrrolidine-2-ones was synthesized by reacting …

Synthesis 4-(((4-ethyl-5-(thiophen-2-yl)-4H-1, 2, 4-triazol-3-yl) thio) methyl)-6, 8-
dimethylcoumarin and spectral analysis is carried out using the FT-IR and NMR with the …

The present paper is devoted to the search for drug-like molecules with anticancer
properties using the thiazolo [3, 2-b][1, 2, 4] triazole-6-one scaffold. A series of 24 novel …

The synthesis of a new hexabromotellurate of triazole ring-containing amino acid is
described. XRD, NMR and DFT analysis of the structure of protonated [(5-amino-4-phenyl-4 …

Understanding the interactions between drugs and enzymes is crucial for designing effective
therapeutics. This study employed a combination of molecular docking and molecular …

Many nitrogen-and sulfur-containing heterocyclic compounds exhibit biological activity.
Among these heterocycles are benzo [4, 5] thiazolo [2, 3-c][1, 2, 4] triazoles for which two …

The synthesis of triazoles has attracted a lot of interest in the field of organic chemistry
because of its versatile chemical characteristics and possible biological uses. This review …