The light microscope is traditionally an instrument of substantial size and expense. Its
miniaturized integration would enable many new applications based on mass-producible …

Counting circular objects such as cell colonies is an important source of information for
biologists. Although this task is often time-consuming and subjective, it is still predominantly …

The potential of stem cells in clinics and as a diagnostic tool is still largely unmet, partially
due to a lack of in vitro models that efficiently mimic the in vivo stem cell microenvironment …

Stratum corneum is the outermost layer of the skin preventing external substances from
entering human body. Microneedles (MNs) are sharp protrusions of a few hundred microns …

Cell counting is a vital practice in the maintenance and manipulation of cell cultures. It is a
crucial aspect of assessing cell viability and determining proliferation rates, which are …

High-throughput droplet microfluidic devices with fluorescence detection systems provide
several advantages over conventional end-point cytometric techniques due to their ability to …

We report a reliable strategy to perform automated image cytometry of single (non-adherent)
stem cells captured in microfluidic traps. The method rapidly segments images of an entire …

Purpose It is known that endothelial cells in the kidney are also strongly VEGF-dependent.
Whether intravitreal drugs can be detected within the glomeruli or affect VEGF in glomerular …

Background Retinal ganglion cell (RGC) loss is one of the earliest and most important
cellular changes in glaucoma. The DARC (Detection of Apoptosing Retinal Cells) …

Cell counting in microscopic images is one of the fundamental analysis tools in life sciences,
but is usually tedious, time consuming and prone to human error. Several programs for …