Impact of oxidative stress on oocyte competence for in vitro embryo production programs

S Soto-Heras, MT Paramio - Research in Veterinary Science, 2020 - Elsevier
Producing high-competent oocytes during the in vitro maturation (IVM) is considered a key
step for the success of the in vitro production (IVP) of embryos. One of the known disruptors …

[HTML][HTML] Reactive oxygen species generation and use of antioxidants during in vitro maturation of oocytes

M Khazaei, F Aghaz - International journal of fertility & sterility, 2017 - ncbi.nlm.nih.gov
In vitro maturation (IVM) is emerging as a popular technology at the forefront of fertility
treatment and preservation. However, standard in vitro culture (IVC) conditions usually …

Melatonin supplementation during in vitro maturation of oocyte enhances subsequent development of bovine cloned embryos

Q An, W Peng, Y Cheng, Z Lu, C Zhou… - Journal of cellular …, 2019 - Wiley Online Library
Oocyte quality, which is directly related to reprogramming competence, is a major important
limiting factor in animal cloning efficiency. Compared with oocytes matured in vivo, in vitro …

Melatonin scavenger properties against oxidative and nitrosative stress: impact on gamete handling and in vitro embryo production in humans and other mammals

P Loren, R Sánchez, ME Arias, R Felmer… - International Journal of …, 2017 - mdpi.com
Oxidative and nitrosative stress are common problems when handling gametes in vitro. In
vitro development in mammalian embryos is highly affected by culture conditions, especially …

Melatonin improves in vitro development of vitrified-warmed mouse germinal vesicle oocytes potentially via modulation of spindle assembly checkpoint-related genes

Z Wu, B Pan, IH Qazi, H Yang, S Guo, J Yang, Y Zhang… - Cells, 2019 - mdpi.com
The present study aimed to investigate the effect of melatonin (MT) supplementation on in
vitro maturation of vitrified mouse germinal vesicle (GV) oocytes. The fresh oocytes were …

Antioxidants supplementation improves the quality of in vitro produced ovine embryos with amendments in key development gene expressions

SK Tripathi, S Nandi, PSP Gupta, S Mondal - Theriogenology, 2023 - Elsevier
The present study assessed the effects of supplementation of different antioxidants on
oocyte maturation, embryo production, reactive oxygen species (ROS) production and …

Melatonin improves the quality of frozen bull semen and influences gene expression related to embryo genome activation

G Su, S Wu, M Wu, L Wang, L Yang, M Du, X Zhao… - Theriogenology, 2021 - Elsevier
The efficiency of animal artificial breeding in vitro is still low. Oxidative damage is an
important obstacle for in vitro artificial breeding of animals. Melatonin can reduce the degree …

Melatonin supplementation during prolonged in vitro maturation improves the quality and development of poor‐quality porcine oocytes via anti‐oxidative and anti …

T Lin, JE Lee, JW Kang, RK Oqani… - Molecular …, 2018 - Wiley Online Library
Poor‐quality oocytes (those with 1–2 layers of cumulus cells) typically possess low meiotic
competence and development. Prolonging the duration of in vitro maturation (IVM; 52 hr) …

Enhancing the developmental competence of prepubertal lamb oocytes by supplementing the in vitro maturation medium with sericin and the fibroblast growth factor 2 …

H Tian, Q Qi, F Yan, C Wang, F Hou, W Ren, L Zhang… - Theriogenology, 2021 - Elsevier
Poor development of oocytes from prepubertal animals is a major factor that hinders the
application of the technology, juvenile in vitro embryo transfer (JIVET). The aim of this study …

Protective effects of melatonin on the in vitro developmental competence of bovine oocytes

Y Pang, S Zhao, Y Sun, X Jiang, H Hao… - Animal Science …, 2018 - Wiley Online Library
The present study investigated the effects of melatonin on bovine oocyte maturation and
subsequent embryonic development in vitro. Results showed that the nuclear and …