By the end of the twentieth century, the interest in natural compounds as probable sources of
drugs has declined and was replaced by other strategies such as molecular target-based …

Covering: up to 2018 With contributions from the global natural product (NP) research
community, and continuing the Raw Data Initiative, this review collects a comprehensive …

Indoles are a significant heterocyclic system in natural products and drugs. They are
important types of molecules and natural products and play a main role in cell biology. The …

Background As one of the most commonly used folk medicines in “Dai” ethno-medicine
system, Alstonia scholaris (l.) R. Br. has also been used for treat" water related diseases" …

Three new monoterpenoid indole alkaloids, named normavacurine-21-one (1), 5-hydroxy-
19, 20-E-alschomine (2), and 5-hydroxy-19, 20-Z-alschomine (3), together with thirteen …

Thousands of known alkaloids contain a nitrogen (N) heterocycle. While five-, six-and seven-
membered N-heterocycles (ie: pyrroles, imidazoles, indoles, pyridines and azepines and …

Covering: up to 2024This review aims to draw a parallel between all known oligomers of
monoterpene indole alkaloids (MIAs) by illustrating the chemical logic underlying their …

Ethnopharmacological relevance Alstonia scholaris (L.) R. Br.(Apocynaceae) is a medicinal
plant in China traditionally used to treat pulmonary diseases, including bronchitis, whooping …

Background Alstonia scholaris is a folk medicine used to treat cough, asthma and chronic
obstructive pulmonary disease in China. Total alkaloids (TA) from A. scholaris exhibit anti …

Abstract Alstonia scholaris (L.) R. Br.(Apocynaceae) is an evergreen tree that has been used
to treat lung diseases. In this study, the toxicity profile of indole alkaloids from leaves of A …