Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Cystathionine beta-synthase (CBS) deficiency is a rare inherited disorder in the methionine
catabolic pathway, in which the impaired synthesis of cystathionine leads to accumulation of …

Cystathionine-β-synthase (CBS), the first (and rate-limiting) enzyme in the transsulfuration
pathway, is an important mammalian enzyme in health and disease. Its biochemical …

Basal-like breast cancer (BLBC) is the most aggressive subtype of breast tumors with poor
prognosis and limited molecular-targeted therapy options. We show that BLBC cells have a …

This review covers briefly the major conditions, genetic and non‐genetic, sometimes leading
to abnormally elevated methionine, with emphasis on recent developments. A major aim is …

Homocystinuria caused by cystathionine β-synthase (CBS) deficiency is characterized by
involvement of the eye (ectopia lentis and/or severe myopia), skeletal system (excessive …

Cysteine and obesity: consistency of the evidence across epi... : Current Opinion in Clinical
Nutrition & Metabolic Care Cysteine and obesity: consistency of the evidence across …

In 2012, the Norwegian newborn screening program (NBS) was expanded (eNBS) from
screening for two diseases to that for 23 diseases (20 inborn errors of metabolism, IEMs) …

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest of all cancer types with a
constant rise in global incidence. Therefore, better understanding of PDAC biology, in order …

Hypothermia and rewarming produces organ injury through the production of reactive
oxygen species. We previously found that dopamine prevents hypothermia and rewarming …