This Review summarizes the advances in the construction of all-carbon quaternary
stereocenters via catalytic enantioselective desymmetrization of prochiral and meso …

The pool of abundant chiral terpene building blocks (ie,“chiral pool terpenes”) has long
served as a starting point for the chemical synthesis of complex natural products, including …

Oxaziridines constitute a subset of a class of versatile oxidants whose characteristic feature
is the presence of two electronegative heteroatoms within a strained three-membered ring …

Covering: 2006 to 2015 C–H functionalization remains one of the frontier challenges in
organic chemistry and drives quite an active area of research. It has recently been applied in …

Covering: up to mid-2019 This review highlights the utilization of biomass-derived building
blocks in the total synthesis of natural products. An overview over several renewable …

The Illicium sesquiterpenes are a family of natural products containing over 100 highly
oxidized and structurally complex members, many of which display interesting biological …

Neurodegenerative diseases and spinal cord injury affect approximately 50 million people
worldwide, bringing the total healthcare cost to over 600 billion dollars per year. Nervous …

Abstract Development of a biologically active secondary metabolite into a useful medicine
requires continuous access to meaningful quantities of material. Although any chemical …

A concise, protecting group-free total synthesis of (−)-fusarisetin A (1) was efficiently
achieved in nine steps from commercially available (S)-(−)-citronellal. The synthetic …

The daphniphyllum alkaloids are a structurally fascinating and remarkably diverse family of
natural products. General strategies for the chemical synthesis of their challenging …