Sex differences in mechanisms of arterial stiffness

JJ DuPont, RM Kenney, AR Patel… - British journal of …, 2019 - Wiley Online Library
Arterial stiffness progressively increases with aging and is an independent predictor of
cardiovascular disease (CVD) risk. Evidence supports that there are sex differences in the …

Cardiovascular risk factors and molecular routes underlying endothelial dysfunction: Novel opportunities for primary prevention

G Benincasa, E Coscioni, C Napoli - Biochemical Pharmacology, 2022 - Elsevier
One of the major challenges of cardiovascular primary prevention approach is the absence
of early biomarkers of endothelial dysfunction which may be useful for identifying at-risk …

Evaluation and management of testosterone deficiency: AUA guideline

JP Mulhall, LW Trost, RE Brannigan, EG Kurtz… - The Journal of …, 2018 - auajournals.org
Purpose: There has been a marked increase in testosterone prescriptions in the past
decade resulting in a growing need to give practicing clinicians proper guidance on the …

Sex differences in vascular aging in response to testosterone

KL Moreau, MC Babcock, KL Hildreth - Biology of sex Differences, 2020 - Springer
Large elastic arterial stiffening and endothelial dysfunction are phenotypic characteristics of
vascular aging, a major risk factor for age-associated cardiovascular diseases. Compared to …

Oxidative stress and inflammation are associated with age-related endothelial dysfunction in men with low testosterone

MC Babcock, LE DuBose, TL Witten… - The Journal of …, 2022 - academic.oup.com
Context Vascular aging, including endothelial dysfunction secondary to oxidative stress and
inflammation, increases the risk for age-associated cardiovascular disease (CVD). Low …

The sex-dependent response to psychosocial stress and ischaemic heart disease

TJ Helman, JP Headrick, NJC Stapelberg… - Frontiers in …, 2023 - frontiersin.org
Stress is an important risk factor for modern chronic diseases, with distinct influences in
males and females. The sex specificity of the mammalian stress response contributes to the …

The interactive effects of age and sex on the neuro‐cardiovascular responses during fatiguing rhythmic handgrip exercise

AW D'Souza, R Takeda, K Manabe… - The Journal of …, 2023 - Wiley Online Library
The impact of age on exercise pressor responses is equivocal, likely because of sex‐
specific neuro‐cardiovascular changes with age. However, assessments of the interactive …

Sex differences in cardiovascular aging and heart failure

A Oneglia, MD Nelson, CNB Merz - Current heart failure reports, 2020 - Springer
Abstract Purpose of the Review This review summarizes sex-related changes in the heart
and vasculature that occur with aging, both in the presence and absence of cardiovascular …

Association of transient endothelial dysfunction induced by mental stress with major adverse cardiovascular events in men and women with coronary artery disease

BB Lima, M Hammadah, JH Kim, I Uphoff… - JAMA …, 2019 - jamanetwork.com
Importance Acute mental stress can result in transient endothelial dysfunction, but the
prognostic relevance of this phenomenon is unknown. Objective To determine the …

The etiology and pathophysiology genesis of benign prostatic hyperplasia and prostate cancer: a new perspective

TJ Phua - Medicines, 2021 - mdpi.com
Background: The etiology of benign prostatic hyperplasia and prostate cancer are unknown,
with ageing being the greatness risk factor. Methods: This new perspective evaluates the …