Neurodegenerative diseases are incurable debilitating disorders characterized by structural
and functional neuronal loss. Approximately 30 million people are affected worldwide, and …

Introduction: Prion diseases are a class of rare and fatal neurodegenerative diseases for
which no cure is currently available. They are characterized by conformational conversion of …

Serpins represent the most broadly distributed superfamily of proteases inhibitors. They
contribute to a variety of physiological functions and any alteration of the serpin-protease …

Chronic neuroinflammation is recognized as a major neuropathological hallmark in a broad
spectrum of neurodegenerative diseases including Alzheimer's, Parkinson's, Frontal …

Prion diseases are fatal neurodegenerative disorders with sporadic, genetic or acquired
etiologies. The molecular alterations leading to the onset and the spreading of these …

Prion diseases are a group of neurodegenerative disorders characterized by the
accumulation of misfolded prion protein (called PrPSc). Although conversion of the cellular …

Background: Hemoglobin is the major protein found in erythrocytes, where it acts as an
oxygen carrier molecule. In recent years, its expression has been reported also in neurons …

Hemoglobin (Hb) is the major protein in erythrocytes and carries oxygen (O 2) throughout
the body. Recently, Hb has been found synthesized in atypical sites, including the brain. Hb …

Sepsis is a disease with a high morbidity and mortality rate. At present, there is a lack of
ideal biomarker prognostic models for sepsis and promising studies using prognostic …

Background The increasing prevalence and expanding geographical range of the chronic
wasting disease (CWD) panzootic in cervids is threatening human, animal, environmental …