The East Asian paradox: an updated position statement on the challenges to the current antithrombotic strategy in patients with cardiovascular disease

HK Kim, US Tantry, SC Smith Jr… - Thrombosis and …, 2021 - thieme-connect.com
East Asian patients have reduced anti-ischemic benefits and increased bleeding risk during
antithrombotic therapies compared with Caucasian patients. As potent P2Y 12 receptor …

Expert consensus document: World Heart Federation expert consensus statement on antiplatelet therapy in East Asian patients with ACS or undergoing PCI

GN Levine, Y Jeong, S Goto… - Nature reviews …, 2014 - search.proquest.com
Guideline recommendations on the use of dual antiplatelet therapy (DAPT) in patients with
acute coronary syndromes and in those undergoing percutaneous coronary intervention …

Antithrombotic therapy and body mass: an expert position paper of the ESC Working Group on Thrombosis

B Rocca, KAA Fox, RA Ajjan, F Andreotti… - European heart …, 2018 - academic.oup.com
The success of trials that have shown net clinical benefits of antithrombotic drugs as well as
the increasing prevalence of cardiovascular diseases in an ageing population have led to …

Racial differences in ischaemia/bleeding risk trade-off during anti-platelet therapy: individual patient level landmark meta-analysis from seven RCTs

J Kang, KW Park, T Palmerini, GW Stone… - Thrombosis and …, 2019 - thieme-connect.com
Background Prolonged dual anti-platelet therapy (DAPT) is intended to reduce ischaemic
events, at the cost of an increased bleeding risk in patients undergoing percutaneous …

[HTML][HTML] Acute coronary syndrome in the Asia-Pacific region

MY Chan, X Du, D Eccleston, C Ma… - international Journal of …, 2016 - Elsevier
More than 4.2 billion inhabitants populate the Asia-Pacific region. Acute coronary syndrome
(ACS) is now a major cause of death and disability in this region with in-hospital mortality …

Randomized comparisons of double-dose clopidogrel or adjunctive cilostazol versus standard dual antiplatelet in patients with high posttreatment platelet reactivity …

YD Tang, W Wang, M Yang, K Zhang, J Chen, S Qiao… - Circulation, 2018 - Am Heart Assoc
Background: Patients undergoing percutaneous coronary intervention react differently to
antiplatelet drugs. Those with low responsiveness to clopidogrel have a higher risk of …

[HTML][HTML] Platelet function and genotype after DES implantation in East Asian patients: rationale and characteristics of the PTRG-DES consortium

AY Her, YH Jeong, BK Kim, HJ Joo, K Chang… - Yonsei medical …, 2022 - ncbi.nlm.nih.gov
Purpose Platelet function test (PFT) results and genotype hold unique prognostic
implications in East Asian patients. The aim of the PTRG-DES (Platelet function and …

[PDF][PDF] The evolving concept of dual antiplatelet therapy after percutaneous coronary intervention: focus on unique feature of East Asian and “Asian Paradox”

J Kang, HS Kim - Korean Circulation Journal, 2018 - synapse.koreamed.org
Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 inhibitor is essential after
percutaneous coronary intervention (PCI), while many studies have focused on determining …

Comparison of short-term clinical outcomes between ticagrelor versus clopidogrel in patients with acute myocardial infarction undergoing successful revascularization; …

KH Park, MH Jeong, Y Ahn, TH Ahn, KB Seung… - International journal of …, 2016 - Elsevier
Background Although ticagrelor has been well-known to improve clinical outcomes in
patients with acute myocardial infarction (AMI) without increased bleeding risk, its clinical …

Safety and Effectiveness of Contemporary P2Y12 Inhibitors in an East Asian Population With Acute Coronary Syndrome: A Nationwide Population‐Based Cohort …

JE Yun, YJ Kim, JJ Park, S Kim, K Park… - Journal of the …, 2019 - Am Heart Assoc
Background Prior reports indicate that the effect of P2Y12 inhibitors may be different in East
Asian patients (“East Asian paradox”); therefore, understanding the outcomes associated …