The emerging field of 3D electron diffraction (3D ED) opens new opportunities for structure
determination from sub-micrometre-sized crystals. Although the foundations of this …

Enantioselectivity of helical aggregation is conventionally directed either by its homochiral
ingredients or by introduction of chiral catalysis. The fundamental question, then, is whether …

Hydrogen bonding, bond polarity, and charges in protein molecules play critical roles in the
stabilization of protein structures, as well as affecting their functions such as enzymatic …

Recent technological advances in cryo electron microscopy (cryo-EM) have led to new
opportunities in the structural biology field. Here we benchmark the performance of two 300 …

Three-dimensional electron diffraction (3D ED) is a measurement and analysis technique in
transmission electron microscopy that is used for determining atomic structures from small …

In cryo-electron microscopy (cryo-EM) data collection, locating a target object is error-prone.
Here, we present a machine learning-based approach with a real-time object locator named …

Three-dimensional electron diffraction (3D ED) has become an effective technique to
determine the structures of submicrometre-(nanometre-) sized crystals. In this work, energy …

Electron 3D crystallography can reveal the atomic structure from undersized crystals of
various samples owing to the strong scattering power of electrons. Here, a direct electron …

The challenge in developing molecule-based electronic materials lies in the uncontrollable
or unpredictable nature of their crystal structures, which are crucial for determining both …

Existing drugs often suffer in their effectiveness due to detrimental side effects, low binding
affinity or pharmacokinetic problems. This may be overcome by the development of distinct …