Nine out of 10 people breathe air that does not meet World Health Organization pollution
limits. Air pollutants include gasses and particulate matter and collectively are responsible …

Over recent years, many environmental pollutant chemicals have been shown to possess
the ability to interfere in the functioning of the endocrine system and have been termed …

Polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs)
consist of 210 kinds of pollutants, 17 of which are highly toxic to humans. PCDD/F is mainly …

The key characteristics (KC) of human carcinogens provide a uniform approach to
evaluating mechanistic evidence in cancer hazard identification. Refinements to the …

Abstract TCDD (2, 3, 7, 8-tetrachlorodibenzo-p-dioxin) and BDE-209 (decabromodiphenyl
ether) are persistent organic pollutants (POPs) produced by industrial activities and …

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor with important
functions in the immune response and cancer. AHR agonists are provided by the …

Dioxins and analogous derivatives pose significant concerns due to their impact on human
health through both acute and prolonged exposures. They have the potential to resist …

Animal and epidemiological studies demonstrated association of persistent exposure of
TCDD, an endocrine disrupting chemical, to susceptibility of type 2 diabetes (T2D). High …

Dioxin-like compounds (DLCs) are environmental xenobiotics that can activate the aryl
hydrocarbon receptors (AhR), thereby imposing a significant threat to human health through …

Water sources are frequently contaminated with natural and anthropogenic substances
having known or suspected endocrine disrupting activities; however, these activities are not …