Healthy ageing: Herpes zoster infection and the role of zoster vaccination

D Curran, TM Doherty, N Lecrenier, T Breuer - npj Vaccines, 2023 - nature.com
Populations are ageing worldwide, with considerable time lived in ill-health, putting upwards
pressure on healthcare budgets. Healthy ageing is defined as maintaining functional ability …

[PDF][PDF] The recombinant shingles vaccine is associated with lower risk of dementia

M Taquet, Q Dercon, JA Todd, PJ Harrison - Nature Medicine, 2024 - nature.com
There is emerging evidence that the live herpes zoster (shingles) vaccine might protect
against dementia. However, the existing data are limited and refer only to the live vaccine …

Alzheimer's disease risk reduction in clinical practice: a priority in the emerging field of preventive neurology

K Niotis, C Saperia, N Saif, C Carlton… - Nature Mental …, 2024 - nature.com
Alzheimer's disease is increasing in prevalence disproportionately to longevity, placing
enormous burden on individuals, families, healthcare systems and the economy …

Infection burden, periodontal pathogens, and their interactive association with incident all‐cause and Alzheimer's disease dementia in a large national survey

MA Beydoun, HA Beydoun, DW Hedges… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Relationships and interplay of an infection burden (IB) and periodontal
pathogens or periodontal disease (Pd) markers with Alzheimer's disease (AD) and all‐cause …

Vaccines and dementia: Part II. Efficacy of BCG and other vaccines against dementia

CL Greenblatt, R Lathe - Journal of Alzheimer's Disease, 2024 - content.iospress.com
There is growing awareness that infections may contribute to the development of senile
dementia including Alzheimer's disease (AD), and that immunopotentiation is therefore a …

Herpes zoster and long-term risk of subjective cognitive decline

TS Yeh, GC Curhan, BP Yawn, WC Willett… - Alzheimer's Research & …, 2024 - Springer
Background Herpes zoster (HZ), commonly known as “shingles,” may contribute to cognitive
decline through mechanisms such as neuroinflammation or direct neuronal injury. However …

[HTML][HTML] Pneumococcal vaccination, but not influenza vaccination, is negatively associated with incident dementia among Japanese older adults: The JAGES 2013 …

K Iwai-Saito, K Sato, M Fujii, K Kondo - Brain, Behavior, and Immunity, 2024 - Elsevier
Background It is unclear whether inactivated influenza vaccination (IIV) or pneumococcal
vaccination are associated with the risk of dementia; however, both types of vaccination are …

Alzheimer's disease approaches-Focusing on pathology, biomarkers and clinical trial candidates

J Hroudová, Z Fišar - Progress in Neuro-Psychopharmacology and …, 2024 - Elsevier
The strategy for the development of new drugs for Alzheimer's disease (AD) recognizes that
an effective therapy requires early therapeutic intervention and a multifactorial approach that …

[HTML][HTML] The effect of herpes zoster vaccination at different stages of the disease course of dementia: Two quasi-randomized studies

M Xie, M Eyting, C Bommer, H Ahmed… - medRxiv, 2024 - pmc.ncbi.nlm.nih.gov
The varicella zoster virus, a neurotropic herpesvirus, has been hypothesized to play a role in
the pathophysiology of dementia, such as through neuroinflammatory processes or …

Recombinant zoster vaccine and the risk of dementia

E Tang, I Ray, BF Arnold, NR Acharya - Vaccine, 2025 - Elsevier
Background Herpes zoster is a potential risk factor for dementia. The effectiveness of the
recombinant zoster vaccine for preventing dementia is uncertain. Methods This retrospective …