Species of the genus Trichoderma inhabit diverse environments and undergo a variety of
interactions with different other organisms. Mycoparasitic Trichoderma species are …

Many Fungi have a well-developed secondary metabolism. The diversity of fungal species
and the diversification of biosynthetic gene clusters underscores a nearly limitless potential …

Secondary metabolites (SMs) produced by filamentous fungi possess diverse bioactivities
that make them excellent drug candidates. Whole genome sequencing has revealed that …

High throughput genome sequencing has revealed a multitude of potential secondary
metabolites biosynthetic pathways that remain cryptic. Pathway reconstruction coupled with …

Highlights•Aspergillus terreus is a valuable filamentous fungus with excellent synthetic
capacity for natural products.•A number of new secondary metabolites with pharmaceutical …

In recent decades, biocatalysis has attracted more and more attention, contributing
significantly to synthetic organic chemistry and biotechnology and thereby advancing the …

Aspergillus is a genus of ubiquitous fungi that are therapeutically important because the
genus produces a wide range of structurally diverse secondary metabolites that are of highly …

Spore pigmentation is very common in the fungal kingdom. The best studied pigment in
fungi is melanin which coats the surface of single cell spores. What and how pigments …

Background Non-ribosomal peptide synthetase-like (NRPS-like) enzymes are highly
enriched in fungal genomes and can be discriminated into reducing and non-reducing …

Abnormal vasoconstriction, inflammation, and vascular remodeling can be promoted by
angiotensin II (Ang II) in the renin–angiotensin system (RAS), leading to vascular …