The kidney maintains electrolyte, water, and acid-base balance, eliminates foreign and
waste compounds, regulates blood pressure, and secretes hormones. There are at least 16 …

Until recently, significant advances in our understanding of the mechanisms of blood
pressure regulation arose from studies of monogenic forms of hypertension and …

Gut microbiota in hypertension : Current Opinion in Nephrology and Hypertension Gut
microbiota in hypertension : Current Opinion in Nephrology and Hypertension Log in or …

Hypertension is a significant and increasing global health issue. It is a leading cause of
cardiovascular disease and premature death worldwide due to its effects on end organs …

Uromodulin (or Tamm-Horsfall protein) is a glycoprotein uniquely produced in the kidney by
tubular cells of the thick ascending limb of the loop of Henle and early distal tubules. This …

Aims Coronary artery disease (CAD) is multifactorial, caused by complex pathophysiology,
and contributes to a high burden of mortality worldwide. Urinary proteomic analyses may …

Tamm–Horsfall protein (THP), or uromodulin (UMOD), is an 80–90-kDa phosphatidylinositol-
anchored glycoprotein produced exclusively by the renal tubular cells in the thick ascending …

Hypertension (HTN) affects about 1 billion people worldwide and the lack of a single
identifiable cause complicates its treatment. Blood pressure (BP) levels are influenced by …

Hypertension management poses a major challenge to clinicians globally once non-drug
(lifestyle) measures have failed to control blood pressure (BP). Although drug treatment …

Hypertension is a significant risk factor for cardiovascular disease and mortality worldwide.
The kidney is a major regulator of blood pressure and electrolyte homeostasis, with …