MiT family translocation renal cell carcinoma: from the early descriptions to the current knowledge
The new category of MiT family translocation renal cell carcinoma has been included into
the World Health Organization (WHO) classification in 2016. The MiT family translocation …
the World Health Organization (WHO) classification in 2016. The MiT family translocation …
Translocation carcinomas of the kidney
P Argani - Genes, Chromosomes and Cancer, 2022 - Wiley Online Library
The MiT subfamily of transcription factors includes TFE3, TFEB, TFEC, and MITF. Gene
fusions involving two of these transcription factors have been well‐characterized in renal cell …
fusions involving two of these transcription factors have been well‐characterized in renal cell …
[HTML][HTML] New developments in existing WHO entities and evolving molecular concepts: The Genitourinary Pathology Society (GUPS) update on renal neoplasia
K Trpkov, O Hes, SR Williamson, AJ Adeniran… - Modern Pathology, 2021 - Elsevier
Abstract The Genitourinary Pathology Society (GUPS) reviewed recent advances in renal
neoplasia, particularly post-2016 World Health Organization (WHO) classification, to provide …
neoplasia, particularly post-2016 World Health Organization (WHO) classification, to provide …
Report from the international society of urological pathology (ISUP) consultation conference on molecular pathology of urogenital cancers: III: molecular pathology of …
Renal cell carcinoma (RCC) subtypes are increasingly being discerned via their molecular
underpinnings. Frequently this can be correlated to histologic and immunohistochemical …
underpinnings. Frequently this can be correlated to histologic and immunohistochemical …
[HTML][HTML] Detection of 6 TFEB-amplified renal cell carcinomas and 25 renal cell carcinomas with MITF translocations: systematic morphologic analysis of 85 cases …
SL Skala, H Xiao, AM Udager, SM Dhanasekaran… - Modern Pathology, 2018 - Elsevier
Renal cell carcinomas with MITF aberrations demonstrate a wide morphologic spectrum,
highlighting the need to consider these entities within the differential diagnosis of renal …
highlighting the need to consider these entities within the differential diagnosis of renal …
[HTML][HTML] TFEB-VEGFA (6p21. 1) co-amplified renal cell carcinoma: a distinct entity with potential implications for clinical management
S Gupta, SH Johnson, G Vasmatzis, B Porath… - Modern Pathology, 2017 - Elsevier
A subset of renal cell carcinomas shows TFEB overexpression secondary to MALAT1-TFEB
gene fusion. As alternate mechanisms of TFEB overexpression are likely to have the same …
gene fusion. As alternate mechanisms of TFEB overexpression are likely to have the same …
Clinicopathologic and molecular analysis of the TFEB fusion variant reveals new members of TFEB translocation renal cell carcinomas (RCCs): expanding the …
QY Xia, XT Wang, R Fang, Z Wang… - The American Journal …, 2020 - journals.lww.com
Xp11 renal cell carcinoma (RCC) with different gene fusions may have different
clinicopathologic features. We sought to identify variant fusions in TFEB translocation RCC …
clinicopathologic features. We sought to identify variant fusions in TFEB translocation RCC …
Cathepsin K: a novel diagnostic and predictive biomarker for renal tumors
Simple Summary Our understanding of renal tumors has increased in the last years with the
description of several novel entities. The expanding morphological spectrum complicates …
description of several novel entities. The expanding morphological spectrum complicates …
TFE3 and TFEB-rearranged renal cell carcinomas: an immunohistochemical panel to differentiate from common renal cell neoplasms
TFE3/TFEB-rearranged renal cell carcinomas are characterized by translocations involving
TFE3 and TFEB genes. Despite the initial description of typical morphology, their histological …
TFE3 and TFEB genes. Despite the initial description of typical morphology, their histological …
TFEB expression profiling in renal cell carcinomas: clinicopathologic correlations
TFEB is overexpressed in TFEB-rearranged renal cell carcinomas as well as in renal tumors
with amplifications of TFEB at 6p21. 1. As recent literature suggests that renal tumors with …
with amplifications of TFEB at 6p21. 1. As recent literature suggests that renal tumors with …