Tissue-specific features of innate lymphoid cells in antiviral defense
SJ Piersma - Cellular & Molecular Immunology, 2024 - nature.com
Innate lymphocytes (ILCs) rapidly respond to and protect against invading pathogens and
cancer. ILCs include natural killer (NK) cells, ILC1s, ILC2s, ILC3s, and lymphoid tissue …
cancer. ILCs include natural killer (NK) cells, ILC1s, ILC2s, ILC3s, and lymphoid tissue …
Beta actin G342D as a cause of natural killer cell deficiency impairing lytic synapse termination
AE Reed, J Peraza, F van den Haak… - Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Natural killer (NK) cell deficiency (NKD) occurs when an individual's major clinical
immunodeficiency derives from abnormal NK cells and is associated with several genetic …
immunodeficiency derives from abnormal NK cells and is associated with several genetic …
[HTML][HTML] Splice site and de novo mutations can cause mixed dominant negative/gain of function PLCG2-associated immune dysregulation with cold urticaria (CU …
Background: Phospholipase Cγ2 (PLCγ2) is an important signaling molecule that receives
and transmits signals from various cell surface receptors in most hematopoietic lineages …
and transmits signals from various cell surface receptors in most hematopoietic lineages …
Splice site and de novo mutations can cause mixed gain of function/dominant negative PLCG2-associated immune dysregulation with cold urticaria (CU-PLAID)
Background: Phospholipase Cγ2 (PLCγ2) is an important signaling molecule that receives
and transmits signals from various cell surface receptors in most hematopoietic lineages …
and transmits signals from various cell surface receptors in most hematopoietic lineages …
Splice site and de novo variants can cause PLCG2-associated immune dysregulation with cold urticaria
SR Chou, AC Bailey, K Baysac, AJ Oler… - Journal of Allergy and …, 2024 - Elsevier
Background Phospholipase Cγ2 (PLCγ2) is an important signaling molecule that receives
and transmits signals from various cell surface receptors in most hematopoietic lineages …
and transmits signals from various cell surface receptors in most hematopoietic lineages …
PLCG2 variants in cherubism
JG Chester, B Carcamo, DA Gudis… - Journal of Allergy and …, 2024 - Elsevier
Background Cherubism is most commonly caused by rare heterozygous gain-of-function
(GOF) missense variants in SH3BP2, which appear to signal through phospholipase C …
(GOF) missense variants in SH3BP2, which appear to signal through phospholipase C …
Spectrum of clinical phenotypes of PLCG2 gene variants: Just PLAID
J Chinen - Journal of Allergy and Clinical Immunology, 2024 - jacionline.org
Clinicians are advised to be cautious of associating a newly found gene variant with a
syndrome that has been previously reported with other pathogenic variants in the same …
syndrome that has been previously reported with other pathogenic variants in the same …
[HTML][HTML] ПЕРВИННІ МІНОРНІ ІМУНОДЕФІЦИТИ ЯК ПРИЧИНА РОЗВИТКУ ІМУНОЗАЛЕЖНОЇ ПАТОЛОГІЇ У ЛЮДЕЙ: ЕТІОЛОГІЯ, ЕПІДЕМІОЛОГІЯ …
D Maltsev - Immunology and Allergology: Science and Practice, 2024 - immunology.org.ua
Backgrounds. Primary minor immunodeficiencies (PMD) occur in the human population
more often than classical immunodeficiencies and make a great burden on society …
more often than classical immunodeficiencies and make a great burden on society …
Modeling of NK Cells in Pediatric Patients With Unusually Severe or Recurrent HSV Using High-Dimensional Flow Cytometry
Y Feng - 2024 - openscholarship.wustl.edu
HSV infection is broadly spread all over the world with some patients having severe and/or
recurrent HSV infections. Our lab studies human Natural Killer (NK) cells, which are …
recurrent HSV infections. Our lab studies human Natural Killer (NK) cells, which are …
Human PLCG2 haploinsufficiency results in a novel NK cell immunodeficiency
A Condino-Neto - Journal of Allergy and Clinical Immunology, 2024 - jacionline.org
In this study, Alinger et al. advance our understanding of PLCG2 genetic variants and their
clinical implications (1). PLCG2-associated antibody deficiency and immune dysregulation …
clinical implications (1). PLCG2-associated antibody deficiency and immune dysregulation …