Networks are one of the most common ways to represent biological systems as complex sets
of binary interactions or relations between different bioentities. In this article, we discuss the …

As research laboratories and clinics collaborate to achieve precision medicine, both
communities are required to understand mandated electronic health/medical record …

Despite considerable progress in genome-and proteome-based high-throughput screening
methods and in rational drug design, the increase in approved drugs in the past decade did …

Computational analysis and interactive visualization of biological networks and protein
structures are common tasks for gaining insight into biological processes. This protocol …

High-throughput studies of biological systems are rapidly accumulating a wealth of'omics'-
scale data. Visualization is a key aspect of both the analysis and understanding of these …

The latest advances in high-throughput techniques during the past decade allowed the
systems biology field to expand significantly. Today, the focus of biologists has shifted from …

Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …

Many algorithms for graph layout have been devised over the last 30 years spanning both
the graph drawing and information visualisation communities. This article first reviews the …

FlyMine is a data warehouse that addresses one of the important challenges of modern
biology: how to integrate and make use of the diversity and volume of current biological …

One of the challenges raised by next generation sequencing (NGS) is the identification of
clinically relevant mutations among all the genetic variation found in an individual. Network …