Hypoxia is a state of low oxygen tension found in numerous solid tumours. It is typically
associated with abnormal vasculature, which results in a reduced supply of oxygen and …

Alzheimer's disease (AD) is one of the most prevalent neurodegenerative disorders with
notable factor of dysfunction in cholinergic system. Low ACh level can be observed in the …

A novel and efficient visible-light-induced C (sp2)–H/N–H cross-dehydrogenative coupling
(CDC)-amination with both primary and secondary aliphatic amines at room temperature in …

A visible light-mediated direct C–H arylation of quinoxalin-2 (1H)-ones with aryl acyl
peroxides has been developed. The reaction proceeds smoothly through a radical process …

A visible-light-initiated α-perfluoroalkyl-β-heteroarylation of various alkenes with
perfluoroalkyl iodides and quinoxalin-2 (1 H)-ones is presented. This three-component …

A photocatalyst-free visible-light-promoted sulfenylation of quinoxalinones with thiols via
cross-dehydrogenative coupling was developed. This protocol allowed the direct formation …

The first example of oxidative C–H fluoroalkoxylation of quinoxalinones with fluoroalkyl
alcohols under transition-metal and solvent-free conditions is described. This approach …

A convenient and efficient transition-metal-free protocol for the synthesis of 3-alkyl
quinoxalin-2 (1H)-ones from the radical reaction of quinoxalin-2 (1H)-ones with ethers was …

A transition metal‐free direct C‐3 arylation of quinoxalin‐2 (1H)‐ones with arylamines has
been explored. This reaction proceeded smoothly through a radical process under mild …

Systemic cytotoxic (anti-proliferative) anticancer drugs rely primarily for their therapeutic
effect on cytokinetic differences between cancer and normal cells. One approach aimed at …