Green chemistry in the synthesis of pharmaceuticals

S Kar, H Sanderson, K Roy, E Benfenati… - Chemical …, 2021 - ACS Publications
The principles of green chemistry (GC) can be comprehensively implemented in green
synthesis of pharmaceuticals by choosing no solvents or green solvents (preferably water) …

Enantioselective radical reactions using chiral catalysts

S Mondal, F Dumur, D Gigmes, MP Sibi… - Chemical …, 2022 - ACS Publications
Benefiting from the impressive increase in fundamental knowledge, the last 20 years have
shown a continuous burst of new ideas and consequently a plethora of new catalytic …

P-Stereogenic phosphorus ligands in asymmetric catalysis

T Imamoto - Chemical reviews, 2024 - ACS Publications
Chiral phosphorus ligands play a crucial role in asymmetric catalysis for the efficient
synthesis of useful optically active compounds. They are largely categorized into two …

Organic synthesis with the most abundant transition metal–iron: from rust to multitasking catalysts

S Rana, JP Biswas, S Paul, A Paik… - Chemical Society Reviews, 2021 - pubs.rsc.org
In industries and academic laboratories, several late transition metal-catalyzed prerequisite
reactions are widely performed during single and multistep synthesis. However, besides the …

Paired electrolysis-enabled nickel-catalyzed enantioselective reductive cross-coupling between α-chloroesters and aryl bromides

D Liu, ZR Liu, ZH Wang, C Ma, S Herbert… - Nature …, 2022 - nature.com
Electrochemical asymmetric catalysis has emerged as a sustainable and promising
approach to the production of chiral compounds and the utilization of both the anode and …

The persistent radical effect in organic synthesis

D Leifert, A Studer - Angewandte Chemie International Edition, 2020 - Wiley Online Library
Radical–radical couplings are mostly nearly diffusion‐controlled processes. Therefore, the
selective cross‐coupling of two different radicals is challenging and not a synthetically …

Metal-Catalyzed Enantioconvergent Transformations

M Yus, C Nájera, F Foubelo, JM Sansano - Chemical Reviews, 2023 - ACS Publications
Enantioconvergent catalysis has expanded asymmetric synthesis to new methodologies
able to convert racemic compounds into a single enantiomer. This review covers recent …

Ligand development for copper-catalyzed enantioconvergent radical cross-coupling of racemic alkyl halides

XY Dong, ZL Li, QS Gu, XY Liu - Journal of the American Chemical …, 2022 - ACS Publications
The enantioconvergent cross-coupling of racemic alkyl halides represents a powerful tool for
the synthesis of enantioenriched molecules. In this regard, the first-row transition metal …

Copper-catalyzed radical relay for asymmetric radical transformations

F Wang, P Chen, G Liu - Accounts of Chemical Research, 2018 - ACS Publications
Conspectus The direct transformation of C–H bonds into diverse functional groups
represents one of the most atom-and step-economical strategies for organic synthesis and …

Recent Advances in Mn, Fe, Co, and Ni-Catalyzed Organic Reactions

LJ Li, Y He, Y Yang, J Guo, Z Lu, C Wang… - CCS …, 2024 - chinesechemsoc.org
This paper reviewed the recent research progress of organic reactions catalyzed by four
typical earth-abundant and 3d metal catalysts: Mn, Fe, Co, and Ni complexes and mainly …