Exploiting solid lipid nanoparticles and nanostructured lipid carriers for drug delivery against cutaneous fungal infections

VHS Araujo, L Delello Di Filippo, JL Duarte… - Critical reviews in …, 2021 - Taylor & Francis
Several types of cutaneous fungal infections can affect the population worldwide, such as
dermatophytosis, cutaneous candidiasis, onychomycosis, and sporotrichosis. However, oral …

Immunity and treatment of sporotrichosis

LC Garcia Carnero, NE Lozoya Perez… - Journal of Fungi, 2018 - mdpi.com
Species of the Sporothrix complex are the etiological agents of sporotrichosis, an important
subcutaneous mycosis with several clinical forms and an increasing incidence around the …

The NLRP3 inflammasome contributes to host protection during Sporothrix schenckii infection

AC Gonçalves, LS Ferreira, FA Manente… - …, 2017 - Wiley Online Library
Sporotrichosis is a mycosis caused by fungi from the Sporothrix schenckii species complex,
whose prototypical member is Sporothrix schenckii sensu stricto. Pattern recognition …

Sporothrix brasiliensis induces a more severe disease associated with sustained Th17 and regulatory T cells responses than Sporothrix schenckii sensu stricto in …

A Batista-Duharte, D Téllez-Martínez, CR de Andrade… - Fungal biology, 2018 - Elsevier
Little is known about the differences in the CD4+ T-cell response induced by Sporothrix
schenckii and Sporothrix brasiliensis, the most virulent species that cause sporotrichosis …

Comparative efficacy and toxicity of two vaccine candidates against Sporothrix schenckii using either Montanide™ Pet Gel A or aluminum hydroxide adjuvants in mice

DL Portuondo, A Batista-Duharte, LS Ferreira… - Vaccine, 2017 - Elsevier
Sporotrichosis is an important zoonosis in Brazil and the most frequent subcutaneous
mycosis in Latin America, caused by different Sporothrix species. Currently, there is no …

Dectin-1 expression by macrophages and related antifungal mechanisms in a murine model of Sporothrix schenckii sensu stricto systemic infection

JA Jellmayer, LS Ferreira, FA Manente… - Microbial …, 2017 - Elsevier
The available information about the role of Dectin-1 in sporotrichosis is scarce. Hence, we
aimed to assess Dectin-1 expression by macrophages and the activation of some related …

Experimental sporotrichosis in a cyclophosphamide-induced immunosuppressed mice model

FA Manente, C Quinello, LS Ferreira… - Medical …, 2018 - academic.oup.com
This report describes a model of host resistance for Sporothrix schenckii, an opportunistic
fungi in immunosuppressed mice with cyclophosphamide (CY) to be used in studies of …

A Review on Sporotrichosis and the Emergence of Sporothrix brasiliensis as a Pathogen

AF Valdez, D Corrêa-Junior, JJA Bonilla… - Current Tropical …, 2023 - Springer
Abstract Purpose of Review This review explores sporotrichosis development as a disease
in both cats and humans as well as options for diagnosis and treatment. This work also …

Pentamidine Inhibits the Growth of Sporothrix Schenckii Complex and Exhibits Synergism With Antifungal Agents

RSN Brilhante, VS Pereira, JS Oliveira… - Future …, 2018 - Taylor & Francis
Aim: The purpose of this study was to evaluate the effects of the antileishmanials meglumine
antimoniate and pentamidine against Sporothrix schenckii complex. Materials & methods …

[HTML][HTML] Antifungal and immunomodulatory activity of a novel cochleate for amphotericin B delivery against Sporothrix schenckii

A Batista-Duharte, M Lastre, B Romeu… - International …, 2016 - Elsevier
Introduction: Sporotrichosis is an emergent subcutaneous mycoses caused by species of the
Sporothrix schenckii complex. Amphotericin B (AmB) remains the main antifungal drug for …