microRNA dysregulation in neurodegenerative diseases: A systematic review

CA Juźwik, SS Drake, Y Zhang, N Paradis-Isler… - Progress in …, 2019 - Elsevier
While the root causes for individual neurodegenerative diseases are distinct, many shared
pathological features and mechanisms contribute to neurodegeneration across diseases …

Mitochondria as central regulators of neural stem cell fate and cognitive function

M Khacho, R Harris, RS Slack - Nature Reviews Neuroscience, 2019 - nature.com
Emerging evidence now indicates that mitochondria are central regulators of neural stem
cell (NSC) fate decisions and are crucial for both neurodevelopment and adult …

The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration

D Heras-Sandoval, JM Pérez-Rojas… - Cellular signalling, 2014 - Elsevier
Disruption of autophagy plays an import role in neurodegenerative disorders, where
deficient elimination of abnormal and toxic protein aggregates promotes cellular stress …

Autophagy and apoptosis cascade: which is more prominent in neuronal death?

R Gupta, RK Ambasta, P Kumar - Cellular and molecular life sciences, 2021 - Springer
Autophagy and apoptosis are two crucial self-destructive processes that maintain cellular
homeostasis, which are characterized by their morphology and regulated through signal …

Adult neurogenesis in the mammalian brain: significant answers and significant questions

G Ming, H Song - Neuron, 2011 - cell.com
Adult neurogenesis, a process of generating functional neurons from adult neural
precursors, occurs throughout life in restricted brain regions in mammals. The past decade …

Adult hippocampal neurogenesis and its role in Alzheimer's disease

Y Mu, FH Gage - Molecular neurodegeneration, 2011 - Springer
The hippocampus, a brain area critical for learning and memory, is especially vulnerable to
damage at early stages of Alzheimer's disease (AD). Emerging evidence has indicated that …

SOX transcription factors as important regulators of neuronal and glial differentiation during nervous system development and adult neurogenesis

M Stevanovic, D Drakulic, A Lazic… - Frontiers in molecular …, 2021 - frontiersin.org
The SOX proteins belong to the superfamily of transcription factors (TFs) that display
properties of both classical TFs and architectural components of chromatin. Since the …

Curcumin-Loaded Nanoparticles Potently Induce Adult Neurogenesis and Reverse Cognitive Deficits in Alzheimer's Disease Model via Canonical Wnt/β-Catenin …

SK Tiwari, S Agarwal, B Seth, A Yadav, S Nair… - ACS …, 2014 - ACS Publications
Neurogenesis, a process of generation of new neurons, is reported to be reduced in several
neurodegenerative disorders including Alzheimer's disease (AD). Induction of neurogenesis …

Neuroinflammation and neurogenesis in Alzheimer's disease and potential therapeutic approaches

PS Sung, PY Lin, CH Liu, HC Su, KJ Tsai - International journal of …, 2020 - mdpi.com
In adult brain, new neurons are generated throughout adulthood in the subventricular zone
and the dentate gyrus; this process is commonly known as adult neurogenesis. The …

Effect of Freeze‐Drying on Apple Pomace and Pomegranate Peel Powders Used as a Source of Bioactive Ingredients for the Development of Functional Yogurt

M Ahmed, A Ali, A Sarfraz, Q Hong… - Journal of Food …, 2022 - Wiley Online Library
Agro‐industrial by‐products of fruits have turned into an essential source of bioactive
products. This study examined the effect of freeze‐drying on apple pomace powder (APP) …