Biomarkers in progressive fibrosing interstitial lung disease: optimizing diagnosis, prognosis, and treatment response

WS Bowman, GA Echt, JM Oldham - Frontiers in Medicine, 2021 - frontiersin.org
Interstitial lung disease (ILD) comprises a heterogenous group of diffuse lung disorders that
commonly result in irreversible pulmonary fibrosis. While idiopathic pulmonary fibrosis (IPF) …

Serum biomarkers of lung fibrosis in interstitial pneumonia with autoimmune features—what do we already know?

E Miądlikowska, P Rzepka-Wrona… - Journal of Clinical …, 2021 - mdpi.com
Interstitial pneumonia with autoimmune features (IPAF) belongs to a group of diseases
called interstitial lung diseases (ILDs), which are disorders of a varied prognosis and course …

Evaluation of the diagnostic efficacies of serological markers KL-6, SP-A, SP-D, CCL2, and CXCL13 in idiopathic interstitial pneumonia

M Xue, Z Guo, C Cai, B Sun, H Wang - Respiration, 2019 - karger.com
Background: The objective of this study was to evaluate the diagnostic value of serological
markers Krebs von den Lungen-6 (KL-6), surfactant protein-A (SP-A), SP-D, chemokine …

Celastrol: A lead compound that inhibits SARS‐CoV‐2 replication, the activity of viral and human cysteine proteases, and virus‐induced IL‐6 secretion

CA Fuzo, RB Martins, TFC Fraga‐Silva… - Drug Development …, 2022 - Wiley Online Library
The global emergence of coronavirus disease 2019 (COVID‐19) has caused substantial
human casualties. Clinical manifestations of this disease vary from asymptomatic to lethal …

[HTML][HTML] Krebs von den Lungen-6 and surfactant protein-A in interstitial pneumonia with autoimmune features

M Xue, C Cai, Y Zeng, Y Xu, H Chen, H Hu, L Zhou… - Medicine, 2021 - journals.lww.com
Interstitial pneumonia with autoimmune features (IPAF) is a special subtype of interstitial
lung disease that has received worldwide attention. Krebs von den Lungen-6 (KL-6) and …

A genomic perspective of the aging human and mouse lung with a focus on immune response and cellular senescence

M He, J Borlak - Immunity & Ageing, 2023 - Springer
Background The aging lung is a complex process and influenced by various stressors,
especially airborne pathogens and xenobiotics. Additionally, a lifetime exposure to antigens …

[HTML][HTML] The Chemokine System as a Key Regulator of Pulmonary Fibrosis: Converging Pathways in Human Idiopathic Pulmonary Fibrosis (IPF) and the Bleomycin …

RC Russo, B Ryffel - Cells, 2024 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a chronic and lethal interstitial lung disease (ILD) of
unknown origin, characterized by limited treatment efficacy and a fibroproliferative nature. It …

High Interleukin-13 level is associated with disease stability in interstitial Lung disease

EK Joerns, D Karp, S Zhang, JA Sparks, TN Adams… - Heliyon, 2024 - cell.com
Abstract (144/150 words) Purpose Cytokines can help predict prognosis in interstitial lung
disease (ILD) and to differentiate between ILD subtypes. The objectives of our study were to …

CXCL10 predicts autoimmune features and a favorable clinical course in patients with IIP: post hoc analysis of a prospective and multicenter cohort study

N Enomoto, S Nakai, S Yazawa, Y Mochizuka… - Respiratory …, 2024 - Springer
Background Interstitial pneumonia with autoimmune features (IPAF), which does not meet
any of the criteria for connective tissue diseases (CTD), has been attracting an attention in …

Bronchoalveolar cytokine profile differentiates Pulmonary Langerhans cell histiocytosis patients from other smoking-related interstitial lung diseases

S Barril, P Acebo, P Millan-Billi, A Luque, O Sibila… - Respiratory …, 2023 - Springer
Abstract Background Pulmonary Langerhans cell histiocytosis (PLCH) is a rare interstitial
lung disease (ILD) associated with smoking, whose definitive diagnosis requires the …