A Hybrid drug which comprises the incorporation of two drug pharmacophores in one single
molecule are basically designed to interact with multiple targets or to amplify its effect …

Market implementation of integrated biorefinery requires reliable and advanced processing
units combined with eco-friendly and economically profitable production chains. Future …

A series of novel 1, 2, 3-triazole-dithiocarbamate hybrids were designed, synthesized and
evaluated for anticancer activity against four selected human tumor cell lines (MGC-803 …

Lysine specific demethylase 1 (LSD1), the first identified histone demethylase, plays an
important role in epigenetic regulation of gene activation and repression. The up-regulated …

The enzymatic hydrolysis of glucosinolates (GLs), typical compounds of Cruciferae,
produces molecules with fungitoxic activity. Eleven GLs and their enzymatic hydrolysis …

Dithiocarbamates are considered as an important motif owing to its extensive biological
applications in medicinal chemistry. The synthesis of this framework can easily be achieved …

A metal-free and visible-light-promoted method has been developed for the synthesis of S-
alkyl dithiocarbamates through multicomponent reactions of α-diazoesters, amines and CS2 …

Novel carbamic esters possessing a carbohydrate moiety derived from glycerol or d-glucose
with two N, N-diethyldithiocarbamoyl groups and a series of bisdithiocarbamic esters having …

A series of novel 1, 2, 3-triazole–dithiocarbamate–urea hybrids were designed, synthesized
and their antiproliferative activities against four selected human cancer cell lines were …

A variety of 4-N atom substituted derivatives were synthesized and evaluated for their in vitro
anticancer activities using 4-methylpiperazine-1-carbodithioic acid 3-cyano-3, 3-diphenyl …