Excess reactive oxygen species production and free radical formation can lead to oxidative
stress that can damage cells, tissues, and organs. Cellular oxidative stress is defined as the …

The estrogen-related receptors (ERRs) comprise a small group of orphan nuclear receptor
transcription factors. The ERRα and ERRγ isoforms play a central role in the regulation of …

With numerous structurally diverse indoor contaminants, indoor transformation chemistry
has been largely unexplored. Here, by integrating protein affinity purification and …

According to the World Health Organization (WHO) polycystic ovary syndrome (PCOS)
occurs in 4–8% of women worldwide. The prevalence of PCOS in Indian adolescents is …

The identification of the estrogen-related receptors (ERRs) as the first orphan nuclear
receptors ignited a new era in molecular endocrinology, which led to the discovery of new …

Triacylglycerols (TAG) serve as the predominant form of energy storage in mammalian cells,
and TAG synthesis influences conditions such as obesity, fatty liver, and insulin resistance …

Bisphenol A (BPA) is an endocrine disruptor that displays estrogenic activity. Several reports
suggest that BPA may have estrogen receptor‐independent effects. In zebrafish, 50 μM BPA …

In response to microbial infection, expression of the defensin-like peptide hepcidin (encoded
by Hamp) is induced in hepatocytes to decrease iron release from macrophages. To …

Estrogen-related receptor (ERR) γ is an orphan nuclear hormone receptor that belongs to
the ERR subfamily of transcription factors. No endogenous ligand has been identified to …

Glucose homeostasis is tightly controlled by hormonal regulation of hepatic glucose
production. Dysregulation of this system is often associated with insulin resistance and …