The epithelial barrier theory and its associated diseases

N Sun, I Ogulur, Y Mitamura, D Yazici, Y Pat, X Bu… - Allergy, 2024 - Wiley Online Library
The prevalence of many chronic noncommunicable diseases has been steadily rising over
the past six decades. During this time, over 350,000 new chemical substances have been …

The cytokine milieu of bullous pemphigoid: Current and novel therapeutic targets

R Maglie, F Solimani, D Didona, C Pipitò… - Frontiers in …, 2023 - frontiersin.org
Bullous pemphigoid (BP) is the most common autoimmune bullous disease, characterized
by severe pruritus and skin blistering. The loss of tolerance against Collagen XVII, also …

Evaluation of dupilumab in patients with bullous pemphigoid

L Zhao, Q Wang, G Liang, Y Zhou, N Yiu… - JAMA …, 2023 - jamanetwork.com
Importance Dupilumab is a theoretically novel therapy for bullous pemphigoid (BP).
However, its effectiveness and safety have yet to be confirmed in a large-scale study …

Autoimmune bullous dermatoses

MM Holtsche, K Boch, E Schmidt - JDDG: Journal der …, 2023 - Wiley Online Library
Autoimmune bullous dermatoses (AIBD) are a heterogeneous group of about a dozen
diseases characterized clinically by erosions and blisters and immunopathologically by …

The intriguing links between psoriasis and bullous pemphigoid

CA Maronese, N Cassano, G Genovese, C Foti… - Journal of Clinical …, 2022 - mdpi.com
The coexistence of psoriasis with autoimmune bullous diseases (AIBDs), particularly bullous
pemphigoid (BP), has been documented in case reports and series, as well as in …

Bullous pemphigoid: the role of type 2 inflammation in its pathogenesis and the prospect of targeted therapy

L Zhang, Z Chen, L Wang, X Luo - Frontiers in Immunology, 2023 - frontiersin.org
Bullous pemphigoid (BP) is an autoimmune disease that mainly occurs in the elderly,
severely affecting their health and life quality. Traditional therapy for BP is mainly based on …

Bullous pemphigoid induced by IgG targeting type XVII collagen non‐NC16A/NC15A extracellular domains is driven by Fc gamma receptor‐and complement …

M Pigors, S Patzelt, N Reichhelm… - The Journal of …, 2024 - Wiley Online Library
Bullous pemphigoid (BP) is an autoimmune blistering disease characterized by
autoantibodies targeting type XVII collagen (Col17) with the noncollagenous 16A (NC16A) …

Accurate diagnosis of bullous pemphigoid requires multiple health care visits

P Leisti, A Pankakoski, J Jokelainen… - Frontiers in …, 2023 - frontiersin.org
Introduction Accurate use of diagnostic codes is crucial for epidemiological and genetic
research based on electronic health record (EHR) data. Methods This retrospective study …

Pemphigus‐und Pemphigoid‐Erkrankungen: Klinik, Diagnostik und Therapie: Pemphigus and pemphigoids: Clinical presentation, diagnosis and therapy

D Didona, MF Schmidt, R Maglie… - JDDG: Journal der …, 2023 - Wiley Online Library
Pemphigus und Pemphigoid sind seltene Autoimmunkrankheiten der Haut mit potenziell
lebensbedrohlichem Verlauf. Autoantikörper gegen epidermale und junktionale …

Immune cells in pemphigus vulgaris and bullous Pemphigoid: From pathogenic roles to targeting therapies

Q Yuan, W Yang, X Zhang - International Immunopharmacology, 2023 - Elsevier
Pemphigus vulgaris (PV) and bullous pemphigoid (BP) are two major subtypes of
autoimmune bullous diseases (AIBD), characterized by blisters and erosions of skin and/or …