Sex/gender differences in the time-course for the development of substance use disorder: a focus on the telescoping effect

EB Towers, IL Williams, EI Qillawala, EF Rissman… - Pharmacological …, 2023 - Elsevier
Sex/gender effects have been demonstrated for multiple aspects of addiction, with one of the
most commonly cited examples being the “telescoping effect” where women meet criteria …

Sex differences in antidepressant efficacy

TA LeGates, MD Kvarta, SM Thompson - Neuropsychopharmacology, 2019 - nature.com
Sex differences have been observed across many psychiatric diseases, especially mood
disorders. For major depression, the most prevalent psychiatric disorder, females show a …

Towards a unified analysis of brain maturation and aging across the entire lifespan: A MRI analysis

P Coupé, G Catheline, E Lanuza… - Human brain …, 2017 - Wiley Online Library
There is no consensus in literature about lifespan brain maturation and senescence, mainly
because previous lifespan studies have been performed on restricted age periods and/or …

Sex differences in the neurobiology of drug addiction

SAM Bobzean, AK DeNobrega, LI Perrotti - Experimental neurology, 2014 - Elsevier
Epidemiological data demonstrate that while women report lower rates of drug use than
men, the number of current drug users and abusers who are women continues to increase …

From glutamate co-release to vesicular synergy: vesicular glutamate transporters

S El Mestikawy, Å Wallén-Mackenzie… - Nature Reviews …, 2011 - nature.com
Recent data indicate that'classical'neurotransmitters can also act as co-transmitters. This
notion has been strengthened by the demonstration that three vesicular glutamate …

Recent perspectives on sex differences in compulsion-like and binge alcohol drinking

AK Radke, EA Sneddon, RM Frasier… - International Journal of …, 2021 - mdpi.com
Alcohol use disorder remains a substantial social, health, and economic problem and
problem drinking levels in women have been increasing in recent years. Understanding …

Sex differences and the role of estradiol in mesolimbic reward circuits and vulnerability to cocaine and opiate addiction

SS Kokane, LI Perrotti - Frontiers in behavioral neuroscience, 2020 - frontiersin.org
Although both men and women become addicted to drugs of abuse, women transition to
addiction faster, experience greater difficulties remaining abstinent, and relapse more often …

Sex differences in synaptic plasticity: hormones and beyond

MM Hyer, LL Phillips, GN Neigh - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Notable sex-differences exist between neural structures that regulate sexually dimorphic
behaviors such as reproduction and parenting. While anatomical differences have been well …

Androgen-dependent excitability of mouse ventral hippocampal afferents to nucleus accumbens underlies sex-specific susceptibility to stress

ES Williams, CE Manning, AL Eagle, A Swift-Gallant… - Biological …, 2020 - Elsevier
Background Depression affects women nearly twice as often as men, but the
neurobiological underpinnings of this discrepancy are unclear. Preclinical studies in male …

Increased reactivity of the paraventricular nucleus of the hypothalamus and decreased threat responding in male rats following psilocin administration

DP Effinger, JL Hoffman, SE Mott, SN Magee… - Nature …, 2024 - nature.com
Psychedelics have experienced renewed interest following positive clinical effects, however
the neurobiological mechanisms underlying effects remain unclear. The paraventricular …