Upper limb motor deficits in severe stroke survivors often remain unresolved over extended
time periods. Novel neurotechnologies have the potential to significantly support upper limb …

Evidence‐based medicine (EBM), by integrating individual clinical expertise with the best
available clinical evidence from systematic research, has in recent years been established …

Background Inflammation is a major contributor to stroke pathology, making it a promising
strategy for intervention. Microglia, the resident macrophages in the brain, play essential …

Importance The underenrollment of women in randomized clinical trials represents a threat
to the validity of the evidence supporting clinical guidelines and potential disparities in …

The 2 classes of drugs that have been most investigated as stroke recovery treatments to
date are serotonergic and dopaminergic. Building on prior smaller studies, the FLAME study …

Puerarin suppresses autophagy to alleviate cerebral ischemia/reperfusion injury, and
accumulating evidence indicates that the AMPK-mTOR signaling pathway regulates the …

Background and purpose Early pharmacological support for post‐stroke neurorehabilitation
has seen an abundance of mixed results from clinical trials, leaving practitioners at a loss …

Stachydrine, a constituent of Leonurus japonicus Houtt which also called Japanese
motherwort has been shown to improve vascular microcirculation and ameliorate …

Background There are few proven treatments for acute spontaneous intracerebral
haemorrhage, and they all target reducing expansion of the haematoma. The traditional …

Background Ischemic stroke (IS) is a leading cause of death and severe long-term disability
worldwide. Over the past few decades, considerable progress has been made in anti …