Osteosarcoma is the most common primary bone malignancy and is a neoplasm thought to
be derived from the bone‐forming mesenchymal stem cells. Aberrant activation of …

Simple Summary Osteosarcomas are heterogeneous bone tumors with complex genetic and
chromosomic alterations. The numerous patients with metastatic osteosarcoma have a very …

As the most prevalent bone tumor in children and adolescents, the pathogenesis and
metastasis of osteosarcoma (OS) remain largely unclear. Here, we investigated the …

The epithelial to mesenchymal transition (EMT) is a cellular process that has been linked to
the promotion of aggressive cellular features in many cancer types. It is characterized by the …

Osteosarcoma (OS) is the most prevalent form of bone cancer. It has a high metastatic
potential and progresses rapidly. The molecular mechanisms of OS remain unclear and this …

Circular RNAs (circRNAs) are generated from'back-splicing'events. Their circular structure
makes them stable in cells and body fluids. These entities are involved in several human …

CircRNAs are reported to exert a significant role in modulating genes in cancers, including
osteosarcoma progression. Up to now, the function of circ_0010220 in osteosarcoma is still …

Emerging evidence indicates that extracellular vesicle (EV)-encapsulated circRNAs have
the potential diagnostic and prognostic values for malignancies. However, the role of …

Osteosarcoma (OS) is one of the most common primary malignant tumors in adolescents. In
recent years, multiple studies have reported the value of miRNAs in the diagnosis of OS, but …

Long noncoding RNAs (lncRNAs) have recently been considered as central regulators in
diverse biological processes controlling tumorigenesis. Small nucleolar RNA host gene 16 …