Developments in nanotechnology have paved the way for the early detection, treatment, and
prevention of several tumors which affect mankind. In the past few years, near-infrared (NIR) …

Oxygen is the third most abundant element in the universe by mass after hydrogen and
helium. It has an atomic number of 8 and is represented by the symbol O. At standard …

RATIONALE AND OBJECTIVE: Deep-tissue optical imaging is of particular interest, as the
equipment costs are lower than for competing technologies such as MRI. For this purpose …

Tumors exhibit fluctuations in blood flow that influence oxygen concentrations and
therapeutic resistance. To assist therapeutic planning and improve prognosis, noninvasive …

Purpose Tissue oxygen (O2) levels are among the most important and most quantifiable
stimuli to which cells and tissues respond through inducible signaling pathways. Tumor O2 …

Aims: In hypoxic tumor microenvironments, the strongly reducing redox environment
reduces evofosfamide (TH-302) to release a cytotoxic bromo-isophosphoramide (Br-IPM) …

A priori knowledge of spatial and temporal changes in partial pressure of oxygen
(oxygenation; pO2) in solid tumors, a key prognostic factor in cancer treatment outcome …

EPR spectra at 250MHz for a single crystal of lithium phthalocyanine (LiPc) in the absence
of oxygen and for a deoxygenated aqueous solution of a Nycomed triarylmethyl (trityl-CD3) …

Significance: Oxygen imaging techniques, which can probe the spatiotemporal
heterogeneity of tumor oxygenation, could be of significant clinical utility in radiation …

Radiation therapy is one of the main modalities to treat cancer/tumor. The response to
radiation therapy, however, can be influenced by physiological and/or pathological …