Viruses are nanoscale entities containing a nucleic acid genome encased in a protein shell
called a capsid and in some cases are surrounded by a lipid bilayer membrane. This review …

Assembly of virus capsids and surface proteins must be regulated to ensure that the
resulting complex is an infectious virion. In this review, we examine assembly of virus …

We develop a class of models with which we simulate the assembly of particles into T1
capsidlike objects using Newtonian dynamics. By simulating assembly for many different …

Viruses play a role in a significant portion of human diseases, as well as those of other
animals, plants, and bacteria. This chapter focuses on the use of theoretical and …

Cowpea chlorotic mottle virus (CCMV) is a widely used model for virus replication studies. A
major challenge lies in distinguishing between the roles of the interaction between coat …

For a three-dimensional structure to spontaneously self-assemble from many identical
components, the steps on the pathway must be kinetically accessible. Many virus capsids …

Computational modeling of assembly is challenging for many systems, because their
timescales can vastly exceed those accessible to simulations. This article describes the …

Virus assembly is a coordinated process in which typically hundreds of subunits react to
form complex, symmetric particles. We use resistive-pulse sensing to characterize the …

The viral protein containers that encapsulate a virus' genetic material are repurposed as
virus-like particles in a host of nanotechnology applications, including cargo delivery …

Understanding the structure and life cycle of viruses is a fascinating challenge with a crucial
impact on the public health sector. In the early 1960s, Caspar & Klug (Caspar & Klug 1962 …