The diverse mechanisms that animals use to resist toxins
RD Tarvin, KC Pearson, TE Douglas… - Annual Review of …, 2023 - annualreviews.org
Biological toxins are entrenched within ecosystems. Thus, animals are often exposed to
such toxins, and how they adapt can be a key determinant of their evolutionary trajectories …
such toxins, and how they adapt can be a key determinant of their evolutionary trajectories …
Convergent evolution of toxin resistance in animals
Convergence is the phenomenon whereby similar phenotypes evolve independently in
different lineages. One example is resistance to toxins in animals. Toxins have evolved …
different lineages. One example is resistance to toxins in animals. Toxins have evolved …
The roles of balancing selection and recombination in the evolution of rattlesnake venom
The origin of snake venom involved duplication and recruitment of non-venom genes into
venom systems. Several studies have predicted that directional positive selection has …
venom systems. Several studies have predicted that directional positive selection has …
[HTML][HTML] Mutual enlightenment: A toolbox of concepts and methods for integrating evolutionary and clinical toxinology via snake venomics and the contextual stance
Snakebite envenoming is a neglected tropical disease that may claim over 100,000 human
lives annually worldwide. Snakebite occurs as the result of an interaction between a human …
lives annually worldwide. Snakebite occurs as the result of an interaction between a human …
Resistance Is not futile: widespread convergent evolution of resistance to alpha-neurotoxic snake venoms in caecilians (Amphibia: Gymnophiona)
Predatory innovations impose reciprocal selection pressures upon prey. The evolution of
snake venom alpha-neurotoxins has triggered the corresponding evolution of resistance in …
snake venom alpha-neurotoxins has triggered the corresponding evolution of resistance in …
[HTML][HTML] Genomic, transcriptomic, and epigenomic analysis of a medicinal snake, Bungarus multicinctus, to provides insights into the origin of Elapidae neurotoxins
J Xu, S Guo, X Yin, M Li, H Su, X Liao, Q Li, L Le… - … Pharmaceutica Sinica B, 2023 - Elsevier
The many-banded krait, Bungarus multicinctus, has been recorded as the animal resource
of JinQianBaiHuaShe in the Chinese Pharmacopoeia. Characterization of its venoms …
of JinQianBaiHuaShe in the Chinese Pharmacopoeia. Characterization of its venoms …
Phenotypic and functional variation in venom and venom resistance of two sympatric rattlesnakes and their prey
Predator–prey interactions often lead to the coevolution of adaptations associated with
avoiding predation and, for predators, overcoming those defences. Antagonistic …
avoiding predation and, for predators, overcoming those defences. Antagonistic …
One Size Fits All—Venomics of the Iberian Adder (Vipera seoanei, Lataste 1878) Reveals Low Levels of Venom Variation across Its Distributional Range
European vipers (genus Vipera) are medically important snakes displaying considerable
venom variation, occurring at different levels in this group. The presence of intraspecific …
venom variation, occurring at different levels in this group. The presence of intraspecific …
Venom gene sequence diversity and expression jointly shape diet adaptation in pitvipers
Understanding the joint roles of protein sequence variation and differential expression
during adaptive evolution is a fundamental, yet largely unrealized goal of evolutionary …
during adaptive evolution is a fundamental, yet largely unrealized goal of evolutionary …
Rapid toxin sequestration modifies poison frog physiology
LA O'Connell… - Journal of …, 2021 - journals.biologists.com
Poison frogs sequester chemical defenses from their diet of leaf litter arthropods for defense
against predation. Little is known about the physiological adaptations that confer this …
against predation. Little is known about the physiological adaptations that confer this …