Electrochemical biosensors based on nucleic acid aptamers

A Villalonga, AM Pérez-Calabuig… - Analytical and bioanalytical …, 2020 - Springer
During recent decades, nucleic acid aptamers have emerged as powerful biological
recognition elements for electrochemical affinity biosensors. These bioreceptors emulate or …

Aptamers in nanostructure-based electrochemical biosensors for cardiac biomarkers and cancer biomarkers: A review

M Negahdary - Biosensors and Bioelectronics, 2020 - Elsevier
Heart disease (especially myocardial infarction (MI)) and cancer are major causes of death.
Recently, aptasensors with the applying of different nanostructures have been able to …

Janus nanoparticles: From fabrication to (bio) applications

X Zhang, Q Fu, H Duan, J Song, H Yang - ACS nano, 2021 - ACS Publications
Janus nanoparticles (JNPs) refer to the integration of two or more chemically discrepant
composites into one structure system. Studies into JNPs have been of significant interest …

A 2D transition metal carbide MXene-based SPR biosensor for ultrasensitive carcinoembryonic antigen detection

Q Wu, N Li, Y Wang, Y Xu, S Wei, J Wu, G Jia… - Biosensors and …, 2019 - Elsevier
Surface plasmon resonance (SPR) has become a leading technique for in situ bioaffinity
assay of diverse targets without need of fluorescent or enzymatic labeling. Nanomaterials …

A review: Recent advances in ultrasensitive and highly specific recognition aptasensors with various detection strategies

SR Yan, MM Foroughi, M Safaei, S Jahani… - International journal of …, 2020 - Elsevier
One of the most studied topics in analytical chemistry and physics is to develop bio-sensors.
Aptamers are small single-stranded RNA or DNA oligonucleotides (5–25 kDa), which have …

Recent developments in aptasensors for diagnostic applications

LS Liu, F Wang, Y Ge, PK Lo - ACS Applied Materials & Interfaces, 2020 - ACS Publications
Aptamers are exciting smart molecular probes for specific recognition of disease biomarkers.
A number of strategies have been developed to convert target–aptamer binding into …

Point-of-care cancer diagnostic devices: From academic research to clinical translation

L Syedmoradi, ML Norton, K Omidfar - Talanta, 2021 - Elsevier
Early and timely diagnosis of cancer plays a decisive role in appropriate treatment and
improves clinical outcomes, improving public health. Significant advances in biosensor …

Electrochemical aptasensors for cancer diagnosis in biological fluids–a review

A Díaz-Fernández, R Lorenzo-Gómez… - Analytica Chimica …, 2020 - Elsevier
The tunability of SELEX procedure is an essential feature to supply bioaffinity receptors
(aptamers) almost on demand for analytical and therapeutic purposes. This longstanding …

Mapping the gaps in chemical analysis for the characterisation of aptamer-target interactions

E Daems, G Moro, R Campos, K De Wael - TrAC Trends in Analytical …, 2021 - Elsevier
Aptamers are promising biorecognition elements with a wide applicability from therapeutics
to biosensing. However, to successfully use these biomolecules, a complete …

Electrokinetic active particles for motion-based biomolecule detection

CP Thome, WS Hoertdoerfer, JR Bendorf, JG Lee… - Nano Letters, 2023 - ACS Publications
Detection of biomolecules is essential for patient diagnosis, disease management, and
numerous other applications. Recently, nano-and microparticle-based detection has been …