Key gaps in the knowledge of the porcine respiratory reproductive syndrome virus (PRRSV)

S Montaner-Tarbes, HA Del Portillo… - Frontiers in veterinary …, 2019 - frontiersin.org
The porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most
important swine diseases in the world. It is causing an enormous economic burden due to …

Effects of PRRSV infection on the porcine thymus

G Wang, Y Yu, X Cai, EM Zhou, JJ Zimmerman - Trends in microbiology, 2020 - cell.com
Porcine reproductive and respiratory syndrome virus (PRRSV) dramatically affects the
thymus and its ability to carry out its normal functions. In particular, infection incapacitates …

The full-length nsp2 replicase contributes to viral assembly in highly pathogenic PRRSV-2

YZ Bai, S Wang, Y Sun, YG Liu, HL Zhang… - Journal of …, 2024 - journals.asm.org
Porcine reproductive and respiratory syndrome viruses (PRRSVs) are significant pathogens
that affect the global swine industry. Its virions consist of a central core composed of …

Development of a blocking enzyme-linked immunosorbent assay for detection of antibodies against African swine fever virus

F Yuan, V Petrovan, LG Gimenez-Lirola, JJ Zimmerman… - Pathogens, 2021 - mdpi.com
The incursion of African swine fever virus (ASFV) into Eurasia presents a threat to the world's
swine industry. Highly sensitive and specific diagnostic assays are urgently needed for rapid …

Ribosome profiling of porcine reproductive and respiratory syndrome virus reveals novel features of viral gene expression

GM Cook, K Brown, P Shang, Y Li, L Soday, AM Dinan… - Elife, 2022 - elifesciences.org
The arterivirus porcine reproductive and respiratory syndrome virus (PRRSV) causes
significant economic losses to the swine industry worldwide. Here we apply ribosome …

Discovery and genome characterization of three new Jeilongviruses, a lineage of paramyxoviruses characterized by their unique membrane proteins

B Vanmechelen, M Bletsa, L Laenen, AR Lopes… - BMC genomics, 2018 - Springer
Background In the past decade, many new paramyxoviruses that do not belong to any of the
seven established genera in the family Paramyxoviridae have been discovered. Amongst …

Regulators of viral frameshifting: more than RNA influences translation events

WD Penn, HR Harrington, JP Schlebach… - Annual review of …, 2020 - annualreviews.org
Programmed ribosomal frameshifting (PRF) is a conserved translational recoding
mechanism found in all branches of life and viruses. In bacteria, archaea, and eukaryotes …

The nsp2 hypervariable region of porcine reproductive and respiratory syndrome virus strain JXwn06 is associated with viral cellular tropism to primary porcine …

J Song, P Gao, C Kong, L Zhou, X Ge, X Guo… - Journal of …, 2019 - Am Soc Microbiol
Porcine reproductive and respiratory syndrome virus (PRRSV) poses a major threat to
global pork production and has been notorious for its rapid genetic evolution in the field. The …

Porcine reproductive and respiratory syndrome virus: immune escape and application of reverse genetics in attenuated live vaccine development

H Wang, Y Xu, W Feng - Vaccines, 2021 - mdpi.com
Porcine reproductive and respiratory syndrome virus (PRRSV), an RNA virus widely
prevalent in pigs, results in significant economic losses worldwide. PRRSV can escape from …

Recent advances in PRRS virus receptors and the targeting of receptor–ligand for control

CM Su, RRR Rowland, D Yoo - Vaccines, 2021 - mdpi.com
Cellular receptors play a critical role in viral infection. At least seven cellular molecules have
been identified as putative viral entry mediators for porcine reproductive and respiratory …