The human gastrointestinal tract harbors a diverse range of microbial species, which helps
to regulate various biological processes such as homeostasis of the gut barrier, stimulation …

Ellagitannins (ETs) are a large group of bioactive compounds found in plant-source foods,
such as pomegranates, berries, and nuts. The consumption of ETs has often been …

L-tryptophan (Trp) contributes to regulating bilateral communication of the gut–brain axis. It
undergoes three major metabolic pathways, which lead to formation of kynurenine …

Grapes provide a rich source of polyphenols and fibers. This study aimed to evaluate the
effect of the daily consumption of 46 g of whole grape powder, providing the equivalent of …

The impact of host–microbiome interactions on cognitive health and disease has received
increasing attention. Microbial-derived metabolites produced in the gut are one of crucial …

Pomegranate (Punica granatum L.) is a polyphenol-rich food and medicinal plant containing
flavonols, anthocyanins, and tannins. Ellagitannins (ETs) are the most abundant …

Previous reports described the antidepressant-like action of the aqueous extract of
pomegranate (Punica granatum: AEPG). Thus we evaluated the effect of AEPG and the main …

A polyphenol-rich diet reduced intestinal permeability (IP) in older adults. Our aim was to
evaluate if participants categorized according to urolithin metabotypes (UMs) exhibited …

Scope Dietary polyphenols can alter the gut microbiota (GM) and promote the production of
bioactive metabolites. Several indoles result of GM metabolism of dietary tryptophan have …

We recently demonstrated that the consumption of mixed tree nuts (MTNs) during caloric
restriction decreased cardiovascular risk factors and increased satiety. Tryptophan (Trp) …