In vitro and in vivo evaluation of probiotic potential and safety assessment of Bacillus coagulans SKB LAB-19 (MCC 0554) in humans and animal healthcare

K Chaudhari, M Mohan, P Saudagar, C Sable… - Regulatory Toxicology …, 2022 - Elsevier
Bacillus coagulans is Gram positive, spore forming and high lactic acid producing bacteria;
however, probiotic and safety assessment of the isolated strain need to be investigated for …

Evaluation of Anti-Diarrheal Activities of the 80% Methanol Extract and Solvent Fractions of Maesa lanceolata Forssk (Myrsinaceae) Leaves in Mice

A Megersa, B Dereje, M Adugna… - Journal of …, 2023 - Taylor & Francis
Background Due to the limits of present antidiarrheal medications, it is critical to seek novel,
safe, and inexpensive antidiarrheal agents. Thus, the goal of this study was to assess the …

Antidiarrheal and Antibacterial Activities of Calpurnia aurea: Benth Seed Different Extracts

A Bogale, H Alemayehu, T Nedi… - Evidence‐Based …, 2022 - Wiley Online Library
Background. Calpurnia aurea is believed to have antidiarrheal potential but with limited
scientific evidence. This study aimed investigating antidiarrheal and antibacterial activity of …

In vivo antidiarrheal activity of the crude extract and solvent fractions of Rhamnus prinoides (Rhamnaceae) leaves

TM Ayele, EC Abebe, ZT Muche, MM Agidew, YS Yimer… - Heliyon, 2023 - cell.com
Background Even though numerous conventional anti-diarrheal agents are available, the
inherent toxicities of the drugs urge the search for alternative drugs that are safe and …

Methanolic Crude Extract of Hagenia abyssinica Possesses Significant Antidiarrheal Effect: Evidence for In Vivo Antidiarrheal Activity

ZD Kifle, SA Atnafie, T Yimer Tadesse… - Evidence‐Based …, 2021 - Wiley Online Library
Background. Hagenia abyssinica is one of the most commonly used medicinal plants for the
treatment of diarrhea in Ethiopia. Therefore, this study aimed to evaluate the antidiarrheal …

Antidiarrheal Effect of 80% Methanol Extract and Fractions of the Roasted Seed of Coffea arabica Linn (Rubiaceae) in Swiss Albino Mice

MA Alemu, Z Birhanu Wubneh… - Evidence‐Based …, 2022 - Wiley Online Library
Background. Globally in 2019, diarrhea was the second leading cause of mortality in
children, accounting for more than half a million under‐five deaths yearly. Several societies …

In Vivo Antidiarrheal Potential of the Leaf Extract of Maytenus addat (Loes.) Sebsebe and Its Major Compound

B Mogose, D Bisrat, K Asres - Journal of Tropical Medicine, 2024 - Wiley Online Library
Diarrhea continues to be one of the top causes of death in children under the age of five,
particularly in developing nations. In Ethiopian traditional medicine, a variety of medicinal …

[HTML][HTML] A pharmacologically pre-contracted smooth muscle bowel model for the study of highly-potent opioid receptor agonists and antagonists

N Amend, H Thiermann, F Worek, T Wille - Toxicology Letters, 2023 - Elsevier
Isolated organ models are a versatile tool for pharmacological and toxicological research.
Small bowel has been used to assess the inhibition of smooth muscle contraction by …

RETRACTED ARTICLE: Investigation of Antibacterial and Anti-Diarrhoeal Activities of 80% Methanol Leaf and Fruit Extract of Leonotis ocymifolia (Burm. F) Iwarsson …

T Mengie Ayele, E Chekol Abebe… - Journal of …, 2021 - Taylor & Francis
Mengie Ayele T, Chekol Abebe E, Bogale Kassie A. J Exp Pharmacol. 2021; 13: 613–626.
The Editor and Publisher of Journal of Experimental Pharmacology wish to retract the …

Evaluation of In Vivo Antidiarrheal Activities of 80% Methanol Extract and Solvent Fractions of Peels of Colocasia esculenta (Araceae)

T Obsa Terfa, F Abera Kebede… - Evidence‐Based …, 2024 - Wiley Online Library
Background. Diarrhea is the common gastrointestinal disorder accounting for 2.5 billion
episodes and 1.5 million deaths annually. Limitations and inaccessibility of currently …