Alzheimer's Disease (AD) is a devastating neurodegenerative disorder of the brain, clinically
characterised by cognitive deficits that gradually worsen over time. There is, at present, no …

Blood and lymphatic vessels are lined by endothelial cells which constantly interact with
their luminal and abluminal extracellular environments. These interactions confer physical …

From microscaled capillaries to millimeter‐sized vessels, human vasculature spans multiple
scales and cell types. The convergence of bioengineering, materials science, and stem cell …

Aims Monocytes play an important role in hypertension. Circulating monocytes in humans
exist as classical, intermediate, and non-classical forms. Monocyte differentiation can be …

Electrochemical sensing based on conventional rigid electrodes has great restrictions for
characterizing biomolecules in deformed cells or soft tissues. The recent emergence of …

The blood–brain barrier (BBB) plays a key role in regulating transport into and out of the
brain. With increasing interest in the role of the BBB in health and disease, there have been …

Objective Arterial stiffness has been associated with evidence of cerebral small vessel
disease (cSVD) and fibrillar β-amyloid (Aβ) deposition in the brain. These complex …

Aortic stiffness increases with advancing age, more than doubling during the human life
span, and is a robust predictor of cardiovascular disease (CVD) clinical events independent …

As global life expectancy increases, age-related brain diseases such as stroke and
dementia have become leading causes of death and disability. The aging of the …

The vascular system is integral for maintaining organ‐specific functions and homeostasis.
Dysregulation in vascular architecture and function can lead to various chronic or acute …