The spectrum of synucleinopathies, including Parkinson's disease (PD), multiple system
atrophy (MSA), and dementia with Lewy bodies (DLB), is characterized by α-synuclein …

Family studies have linked several rare genetic variants to hereditary forms of Parkinson's
disease (PD). In addition to these monogenic forms, many PD cases are associated with …

Mitochondrial dysfunction is a hallmark of idiopathic neurodegenerative diseases, including
Parkinson disease, amyotrophic lateral sclerosis, Alzheimer disease and Huntington …

A hallmark event in neurodegenerative diseases is represented by the misfolding,
aggregation and accumulation of proteins, leading to cellular and network dysfunction …

We wish to express our thoughts on recent articles about α-synuclein seed amplification
assays (SAA) from blood-derived neuronal extracellular vesicles (EV) as a potential …

Parkinson's disease (PD) is the second most common neurodegenerative disease in the
world. Currently, PD is incurable, and the diagnosis of PD mainly relies on clinical …

Accurate differential diagnosis of dementia disorders including Alzheimer disease (AD),
frontotemporal dementia (FTD), dementia with Lewy bodies (DLB), Parkinson disease …

Abstract Background Mutations causing Parkinson's disease (PD) give diverse pathological
phenotypes whose cellular correlates remain to be determined. For example, those with …

Neurodegenerative diseases such as Alzheimer's and Parkinson's are characterized by the
death of neurons in specific brains. α-synuclein (α-Syn) is a key factor in Parkinson's disease …

We thank Bernhardt et al. 1 for suggesting a discussion of our recent and earlier publications
2–5 on the use of α-synuclein (α-syn) seed amplification assay (SAA) using blood-derived …