Abstract Interleukin-32 (IL-32) is a novel cytokine involved in inflammation and cancer
development. IL-32 gene consists of eight small exons, and IL-32 mRNA has nine …

Metastasis is the leading cause of breast cancer–related deaths. Cancer-associated
fibroblasts (CAFs), the predominant stromal cell type in the breast tumour microenvironment …

Abstract Interleukin 32 (IL-32) is a proinflammatory cytokine involved in the development of
several diseases, including cancer. IL-32 is a rather peculiar cytokine because its protein …

Colitis-associated cancer is the subtype of colorectal cancer that is associated with
inflammatory bowel diseases including ulcerative colitis and Crohn's disease. Colorectal …

Abstract Interleukin (IL)-32 is known as a proinflammatory cytokine that is likely involved in
several diseases, including infections, chronic inflammation, and cancer. Since the first …

The interaction of multiple myeloma (MM) cells with macrophages (MΦs) contributes to the
pathophysiology of MM. We previously showed that IL-32 is overexpressed in MM patients …

Bladder cancer is a highly metastatic tumor and one of the most common malignancies
originating in the urinary tract. Despite the efficacy of immune checkpoints, including …

IL-32 is a multifaceted cytokine with a role in infections, autoimmune diseases, and cancer,
and it exerts diverse functions, including aggravation of inflammation and inhibition of virus …

Abstract Interleukin-32 (IL-32) is an interleukin cytokine usually linked to inflammation. In
recent years, it has been found that IL-32 exhibits both pro-and anti-tumor effects. Although …

Alternative splicing is a biological mechanism that enables the synthesis of several isoforms
with different or even opposite functions. This process must be tightly regulated to prevent …