Amyotrophic lateral sclerosis (ALS) is a devastating disease caused by degeneration of
motor neurons. As with all major neurodegenerative disorders, development of disease …

Recent advances in sequencing technologies and collaborative efforts have led to
substantial progress in identifying the genetic causes of amyotrophic lateral sclerosis (ALS) …

The Golgi apparatus is known to underpin many important cellular homeostatic functions,
including trafficking, sorting and modifications of proteins or lipids. These functions are …

Gliomas are the most aggressive primary brain tumors. However, no significant improvement
in survival has been achieved with the addition of temozolomide (TMZ) or radiation as initial …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by the
degeneration of motor neurons in the brain and spinal cord. The causes of ALS are not fully …

Abstract Purpose of Review Amyotrophic lateral sclerosis and frontotemporal dementia (ALS-
FTD) spectrum disorder is a rare fatal disease with strong genetic influences. The …

Aging is accompanied by a host of social and biological changes that correlate with
behavior, cognitive health and susceptibility to neurodegenerative disease. To understand …

Glycosyltransferases represent a large family of enzymes that catalyse the biosynthesis of
oligosaccharides, polysaccharides, and glycoconjugates. A number of studies have …

Glycosyltransferases (GTs) are prevalent across the tree of life and regulate nearly all
aspects of cellular functions. The evolutionary basis for their complex and diverse modes of …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with the progressive
loss of motor neurons, leading to a fatal paralysis. According to whether there is a family …