Pyrazolines are five-membered heterocycles possessing two adjacent nitrogens. They have
attracted significant attention from organic and medicinal chemists due to their potent …

Glioblastoma multiforme (GBM) is the most aggressive (WHO grade IV) form of diffuse
glioma endowed with tremendous invasive capacity. The availability of narrow therapeutic …

Among conventional treatment methodologies, surgery, hyperthermia, radiation, and
chemotherapy have become integral components of treatment for most cancers. Radiation …

Thymoquinone (TQ), the bioactive constituent of Nigella Sativa seeds, is a well-known
natural compound for the management of several types of cancers. The anti-cancer …

In the current study, new benzimidazole-based 1, 3, 4-oxadiazole derivatives have been
synthesized and characterized by NMR, IR, MS, and elemental analysis. The final …

It has been established that pyrazolines and their analogs are pharmacologically active
scaffolds. The pyrazoline moiety is present in several marketed molecules with a wide range …

The incidence of cancer is increasing worldwide, affecting a vast majority of the human
population, therefore, new different anticancer agents are being developed now and their …

Polyphenols and amides isolated from natural products have various biological functions,
such as antioxidant, antimicrobial, anticancer, and antiviral activities, and they are widely …

Two new series of oxadiazole and pyrazoline derivatives were designed and synthesized as
promising EGFR-TK inhibitors. The in vitro antiproliferative activity was studied against three …

Simple Summary Cancer is the deadliest disease affecting humans, with more than 14
million cases and 8 million deaths. A successful therapeutic interception of cancer is …