Metabolic (dysfunction)-associated fatty liver disease in individuals of normal weight

M Eslam, HB El-Serag, S Francque, SK Sarin… - Nature reviews …, 2022 - nature.com
Metabolic (dysfunction)-associated fatty liver disease (MAFLD) affects up to a third of the
global population; its burden has grown in parallel with rising rates of type 2 diabetes …

[HTML][HTML] Insulin Resistance, Non-Alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus: Clinical and Experimental Perspective

I Jung, DJ Koo, WY Lee - Diabetes & metabolism journal, 2024 - synapse.koreamed.org
It has been generally accepted that insulin resistance (IR) and reduced insulin secretory
capacity are the basic pathogenesis of type 2 diabetes mellitus (T2DM). In addition to …

Impact of COVID-19 lockdown on non-alcoholic fatty liver disease and insulin resistance in adults: a before and after pandemic lockdown longitudinal study

ÁA López-González, B Altisench Jane… - Nutrients, 2022 - mdpi.com
Background: Non-alcoholic fatty liver disease is a chronic disease caused by the
accumulation of fat in the liver related to overweight and obesity, insulin resistance …

Autonomic imbalance increases the risk for non-alcoholic fatty liver disease

I Jung, DY Lee, MY Lee, H Kwon, EJ Rhee… - Frontiers in …, 2021 - frontiersin.org
Background Although autonomic imbalance is associated with an increased risk for
metabolic disease, its effects on nonalcoholic fatty liver disease (NAFLD) remains unclear …

Changes in Macronutrients during Dieting Lead to Weight Cycling and Metabolic Complications in Mouse Model

A Charlot, A Bringolf, L Debrut, J Mallard, AL Charles… - Nutrients, 2024 - mdpi.com
Weight cycling is a major challenge in obesity management. Caloric restriction is known to
promote this phenomenon, but the impact of macronutrient changes during dieting remains …

A machine-learned model for predicting weight loss success using weight change features early in treatment

F Shahabi, SL Battalio, AF Pfammatter, D Hedeker… - npj Digital …, 2024 - nature.com
Stepped-care obesity treatments aim to improve efficiency by early identification of non-
responders and adjusting interventions but lack validated models. We trained a random …

Triglyceride and glucose index is a simple and easy‐to‐calculate marker associated with nonalcoholic fatty liver disease

KS Kim, S Hong, HY Ahn, CY Park - Obesity, 2022 - Wiley Online Library
Objective The aim of this study was to evaluate the relationship between the triglyceride and
glucose (TyG) index and nonalcoholic fatty liver disease (NAFLD) using a large, population …

[HTML][HTML] Dulaglutide ameliorates palmitic acid-induced hepatic steatosis by activating FAM3A signaling pathway

J Lee, SW Hong, MJ Kim, SJ Moon… - Endocrinology and …, 2022 - synapse.koreamed.org
Background Dulaglutide, a long-acting glucagon-like peptide-1 receptor agonist (GLP-1RA),
has been shown to reduce body weight and liver fat content in patients with type 2 diabetes …

[HTML][HTML] Long-Term Yo-Yo Dieting Exaggerates Liver Steatosis and Lesions but Preserves Muscle Performance in Male Zebrafish

TC Hsu, CH Chiang, IH Liu, CY Wang… - International Journal of …, 2024 - mdpi.com
Weight regain within one year after weight loss is frequently observed and is referred to as
yo-yo dieting or weight cycling. In this study, we explore the effects of yo-yo dieting on the …

Body weight variability and the risk of liver‐related outcomes in type 2 diabetes and steatotic liver disease: a cohort study

NC Leite, CRL Cardoso, CA Villela‐Nogueira… - …, 2024 - Wiley Online Library
Objective The objective of this study was to evaluate the effects of body weight variability
(BWV) on the occurrence of adverse liver outcomes in individuals with type 2 diabetes (T2D) …