Many physiologic effects of l-glutamate, the major excitatory neurotransmitter in the
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …

Dendrites have always fascinated researchers: from the artistic drawings by Ramon y Cajal
to the beautiful recordings of today, neuroscientists have been striving to unravel the …

In the nervous system, dendrites, branches of neurons that transmit signals between
synapses and soma, play a critical role in processing functions, such as nonlinear …

Nonlinear, multiplication-like operations carried out by individual nerve cells greatly
enhance the computational power of a neural system,–, but our understanding of their …

INTRODUCTION The brain of mammals consists of an enormously dense network of
neuronal wires: the axons and dendrites of nerve cells. Their packing density is so high that …

Working memory is a fundamental feature of biological brains for perception, cognition, and
learning. In addition, learning with working memory, which has been show in conventional …

Emotional arousal enhances perception and memory of high-priority information but impairs
processing of other information. Here, we propose that, under arousal, local glutamate levels …

As semiconductor technology enters the more than Moore era, there exists an apparent
contradiction between the rapidly growing demands for data processing and the visible …

Understanding how individual neurons integrate the thousands of synaptic inputs they
receive is critical to understanding how the brain works. Modeling studies in silico and …

The brain has an extraordinary capacity for memory storage, but how it stores new
information without disrupting previously acquired memories remains unknown. Here we …