Inhaled antimicrobial therapy–barriers to effective treatment
J Weers - Advanced drug delivery reviews, 2015 - Elsevier
Inhaled antibiotics dramatically improve targeting of drug to the site of respiratory infections,
while simultaneously minimizing systemic exposure and associated toxicity. The high local …
while simultaneously minimizing systemic exposure and associated toxicity. The high local …
Characteristics of an ideal nebulized antibiotic for the treatment of pneumonia in the intubated patient
M Bassetti, CE Luyt, DP Nicolau, J Pugin - Annals of intensive care, 2016 - Springer
Gram-negative pneumonia in patients who are intubated and mechanically ventilated is
associated with increased morbidity and mortality as well as higher healthcare costs …
associated with increased morbidity and mortality as well as higher healthcare costs …
Nebulized antibiotics in mechanically ventilated patients: roadmap and challenges
G Poulakou, G Siakallis, S Tsiodras… - Expert Review of Anti …, 2017 - Taylor & Francis
Introduction: Nebulized antibiotics use has become common practice in the therapeutics of
pneumonia in cystic fibrosis patients. There is an increasing interest in their use for …
pneumonia in cystic fibrosis patients. There is an increasing interest in their use for …
Inhaled antimicrobials for ventilator-associated pneumonia: practical aspects
G Poulakou, DK Matthaiou, DP Nicolau, G Siakallis… - Drugs, 2017 - Springer
Positive experience with inhaled antibiotics in pulmonary infections of patients with cystic
fibrosis has paved the way for their utilization in mechanically ventilated, critically ill patients …
fibrosis has paved the way for their utilization in mechanically ventilated, critically ill patients …