Owing to the unique ability of antibodies that bind the membrane proximal region of the
extracellular domain to trigger conformational changes leading to affinity modulation and …

Cell‐cell and cell‐substratum interactions are mediated through several different families of
receptors. In addition to targeting cell adhesion to specific extracellular matrix proteins and …

Platelet/endothelial cell adhesion molecule 1 (PECAM-1; CD31) is crucial to the process of
leukocyte transmigration through intercellular junctions of vascular endothelial cells. A …

The circulatory and migratory properties of white blood cells have evolved to allow efficient
surveillance of tissues for infectious pathogens and rapid accu ญ mulation at sites of injury …

The adhesive interactions of endothelial cells with each other and the adhesion receptors
that mediate these interactions are probably of fundamental importance to the process of …

PECAM-1 is a 130-120-kD integral membrane glycoprotein found on the surface of platelets,
at endothelial intercellular junctions in culture, and on cells of myeloid lineage. Previous …

ABSTRACT Cbfa2 (AML1) encodes the DNA-binding subunit of a transcription factor in the
small family of core-binding factors (CBFs). Cbfa2 is required for the differentiation of all …

Integrins are a class of cell adhesion molecules that participate in cell-cell and cell-
substratum interactions and are present on essentially all human cells. The distribution of …

mAbs were raised in mice against cultured human endothelial cells (EC) and screened by
indirect immunofluorescence for their ability to stain intercellular contacts. One mAb denoted …

Platelet endothelial cell adhesion molecule-1 (PECAM-1) is a 130-kD member of the
immunoglobulin (Ig) superfamily that is expressed on the surface of circulating platelets …