Vitamin E and cancer prevention: Studies with different forms of tocopherols and tocotrienols

CS Yang, P Luo, Z Zeng, H Wang… - Molecular …, 2020 - Wiley Online Library
Abstract α‐Tocopherol (α‐T) is the major form of vitamin E (VE) in animals and has the
highest activity in carrying out the essential antioxidant functions of VE. Because of the …

Nanosized drug delivery systems for breast cancer stem cell targeting

L Lv, Y Shi, J Wu, G Li - International Journal of Nanomedicine, 2021 - Taylor & Francis
Breast cancer stem cells (BCSCs), also known as breast cancer initiating cells, are reported
to be responsible for the initiation, progression, therapeutic resistance, and relapse of breast …

Inhibition of breast cancer growth via miR‐7 suppressing ALDH1A3 activity concomitant with decreasing breast cancer stem cell subpopulation

M Pan, M Li, C You, F Zhao, M Guo… - Journal of cellular …, 2020 - Wiley Online Library
Breast cancer patients with high expression of aldehyde dehydrogenases (ALDHs) cell
population have higher tolerability to chemotherapy since the cells posses a characteristic of …

[HTML][HTML] 6-Methoxymellein isolated from carrot (Daucus carota L.) targets breast cancer stem cells by regulating NF-κB signaling

R Liu, HS Choi, SL Kim, JH Kim, BS Yun, DS Lee - Molecules, 2020 - mdpi.com
The presence of breast cancer stem cells (BCSCs) induces the aggressive progression and
recurrence of breast cancer. These cells are drug resistant, have the capacity to self-renew …

DNMT3A/miR-129-2-5p/Rac1 Is an Effector Pathway for SNHG1 to Drive Stem-Cell-like and Invasive Behaviors of Advanced Bladder Cancer Cells

J Xu, R Yang, J Li, L Wang, M Cohen, DM Simeone… - Cancers, 2022 - mdpi.com
Simple Summary Bladder cancer ranks fourth among the most prevalent cancers in men and
is the most expensive cancer to treat on a per-patient basis. The muscle-invasive form of …

Phosphodiesterase 3A represents a therapeutic target that drives stem cell–like property and metastasis in breast cancer

N Hao, W Shen, R Du, S Jiang, J Zhu, Y Chen… - Molecular Cancer …, 2020 - AACR
Considerable evidence suggests that as breast cancer progresses, genetic and epigenetic
mechanisms contribute to the emergence of self-renewing cells (CSC), which may also arise …

OCT4-mediated transcription confers oncogenic advantage for a subset of gastric tumors with poor clinical outcome

J Pandian, P Panneerpandian, BT Sekar… - Functional & Integrative …, 2022 - Springer
Deregulated transcription programs and signaling pathways are the critical factors involved
in the process of carcinogenesis. Signaling pathway-based classification of tumors is …

Gamma tocopherol, its dimmers, and quinones: Past and future trends

L Zheng, J Jin, L Shi, J Huang, M Chang… - Critical Reviews in …, 2020 - Taylor & Francis
Abstract Gamma-tocopherol (γ-T), the major form of vitamin E in many plant seeds and
products derived from them, has been attracting increasing attention because of its health …

Identification of AP002498. 1 and LINC01871 as prognostic biomarkers and therapeutic targets for distant metastasis of colorectal adenocarcinoma

N Wu, J Chen, T Lin, Z Zhong, M Li, Y Yu… - Cancer …, 2024 - Wiley Online Library
Background Increasing evidence suggests that lncRNA (Long non‐coding RNA, lncRNA)‐
mediated ceRNA (competing endogenous RNA, ceRNA) networks are involved in the …

Involvement of the estrogen and progesterone axis in cancer stemness: elucidating molecular mechanisms and clinical significance

B Chen, P Ye, Y Chen, T Liu, JH Cha, X Yan… - Frontiers in …, 2020 - frontiersin.org
Estrogen and progesterone regulate the growth and development of human tissues,
including the reproductive system and breasts, through estrogen and progesterone …