Psoriasis: which therapy for which patient: focus on special populations and chronic infections

SB Kaushik, MG Lebwohl - Journal of the American Academy of …, 2019 - Elsevier
Despite the availability of several new systemic agents for psoriasis treatment, choosing the
right therapy in certain patient populations can be challenging. There are few up-to-date …

Oxidative stress and lipid mediators modulate immune cell functions in autoimmune diseases

P Wójcik, A Gęgotek, N Žarković… - International journal of …, 2021 - mdpi.com
Autoimmune diseases, including psoriasis, systemic lupus erythematosus (SLE), and
rheumatic arthritis (RA), are caused by a combination of environmental and genetic factors …

Secukinumab demonstrates high efficacy and a favourable safety profile in paediatric patients with severe chronic plaque psoriasis: 52‐week results from a phase 3 …

C Bodemer, A Kaszuba, K Kingo… - Journal of the …, 2021 - Wiley Online Library
Background Secukinumab has demonstrated sustained long‐term efficacy with a favourable
safety profile in various psoriatic disease manifestations in adults. Objectives Here, the …

Clinical use and molecular action of corticosteroids in the pediatric age

G Ferrara, MG Petrillo, T Giani, E Marrani… - International journal of …, 2019 - mdpi.com
Corticosteroids are the mainstay of therapy for many pediatric disorders and sometimes are
life-saving. Both endogenous and synthetic derivatives diffuse across the cell membrane …

A phase 3 open-label, randomized multicenter study to evaluate efficacy and safety of secukinumab in pediatric patients with moderate to severe plaque psoriasis: 24 …

N Magnolo, K Kingo, V Laquer, J Browning… - Journal of the American …, 2022 - Elsevier
Background Psoriasis affects 0.13%-2.1% of children and adolescents. Despite a high
unmet need, the current treatment options approved for pediatric psoriasis are limited …

Methotrexate for inflammatory skin disease in pediatric patients: Consensus treatment guidelines

EC Siegfried, LM Arkin, YE Chiu, AA Hebert… - Pediatric …, 2023 - Wiley Online Library
Methotrexate (MTX) is a readily accessible drug, first used in 1948 and employed for a wide
variety of indications since then. However, despite widespread off‐label use, FDA labeling …

Sustained long‐term efficacy and safety of adalimumab in paediatric patients with severe chronic plaque psoriasis from a randomized, double‐blind, phase III study

D Thaçi, K Papp, D Marcoux, L Weibel… - British Journal of …, 2019 - academic.oup.com
Summary Background Adalimumab (ADA)(Humira®, AbbVie Inc., USA) is approved by the
European Medicines Agency for children aged≥ 4 years with severe plaque psoriasis …

Safety and tolerability of adalimumab for the treatment of psoriasis: a review summarizing 15 years of real-life experience

P Sator - Therapeutic advances in chronic disease, 2018 - journals.sagepub.com
Biologic therapies like adalimumab are the gold standard for psoriasis treatment with
efficacy and safety profiles allowing for long-term treatment. However, adalimumab cannot …

Increasing Access to Effective systemic treatments in patients with moderate-to-severe psoriasis: Narrative Review

G Girolomoni, L Savage, P Gisondi, Å Svensson… - Dermatology and …, 2023 - Springer
Psoriasis is a chronic, immune-mediated inflammatory disease with a worldwide prevalence
ranging between 0.51 and 11.43%. It results in a large clinical and social burden, with …

Management of pediatric plaque psoriasis using biologics

P Lansang, JN Bergman, L Fiorillo, M Joseph… - Journal of the American …, 2020 - Elsevier
Background Psoriasis is a chronic inflammatory disease with clinical manifestations of the
skin that affect adults and children. In adults, biologics have revolutionized the treatment of …